HitPredict

Interactor 1: KGP1 (Q13976)
cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent protein kinase I) (cGKI)
Gene: PRKG1

Interactor 2: COR2B (Q9UQ03)
Coronin-2B (Coronin-like protein C) (Clipin-C) (Protein FC96)
Gene: CORO2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0030036 - actin cytoskeleton organization
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 671 Hs			1 480
+	Hs
		610684 KAPCB_HUMAN (326-656): 7.02e-144: 424: 42.60		COR1A_HUMAN (9-478): 1.38e-109: 334: 43.28
+	Mm
		661011 KPCD_MOUSE (141-668): 1.02e-178: 525: 26.32		FBXW7_MOUSE (2-294): 8.98e-60: 210: 14.62
+	Hs
		498336 KAP0_HUMAN (2-338): 8.18e-132: 395: 31.41		COR1B_HUMAN (6-480): 9.58e-107: 327: 42.17
+	Mm
		554925 KPCE_MOUSE (177-664): 1.24e-169: 504: 24.31		FBXW7_MOUSE (2-294): 8.98e-60: 210: 14.62
+	Ce
		283758 EGL4_CAEEL (1-671): 0: 619: 47.08		LIN53_CAEEL (20-167): 9.52e-13: 71.6: 19.75
+	Hs
		681967 AKT1_HUMAN (243-666): 7.34e-152: 450: 29.66		FBXW7_HUMAN (2-294): 2.8e-59: 209: 14.62
+	Hs
		498325 KAP0_HUMAN (2-338): 8.18e-132: 395: 31.41		SNR40_HUMAN (172-399): 4.86e-39: 146: 10.48
+	Hs
		1083416 KS6B2_HUMAN (333-665): 2.73e-140: 420: 38.17		RBBP7_HUMAN (82-167): 1.41e-12: 71.2: 20.43
+	Hs
		217865 PRKY_HUMAN (346-583): 6.19e-67: 222: 44.54		CORO7_HUMAN (10-421): 5.3e-65: 227: 27.69
+	Mm
		934635 KPCB_MOUSE (177-316): 1.77e-27: 119: 12.06		FBXW7_MOUSE (2-294): 8.98e-60: 210: 14.62
+	Mm
		593490 KPCA_MOUSE (177-358): 4.17e-26: 115: 10.58		FBXW7_MOUSE (2-294): 8.98e-60: 210: 14.62
+	Hs
		850643 KS6A3_HUMAN (360-603): 5.45e-24: 109: 30.47		RBBP4_HUMAN (83-167): 4.07e-12: 69.7: 19.57