HitPredict

Interactor 1: NOTC2 (Q04721)
Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)]
Gene: NOTCH2

Interactor 2: ZN669 (Q96BR6)
Zinc finger protein 669
Gene: ZNF669

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2471 Hs			1 464
+	Hs
		1047607 NOTC2_HUMAN (22-2471): 0: 1400: 100.00		ZSCA2_HUMAN (147-463): 3.2e-167: 486: 42.90
+	Hs
		599953 NOTC2_HUMAN (22-2471): 0: 1400: 100.00		ZN708_HUMAN (88-461): 6.7e-149: 437: 36.04
+	Hs
		1047661 NOTC2_HUMAN (22-2471): 0: 1400: 100.00		ZN431_HUMAN (87-461): 1.05e-138: 412: 35.78
+	Hs
		1047770 NOTC2_HUMAN (22-2471): 0: 1400: 100.00		ZN629_HUMAN (3-386): 9.59e-107: 338: 17.02
+	Hs
		1047742 NOTC2_HUMAN (22-2471): 0: 1400: 100.00		ZN430_HUMAN (112-378): 1.38e-99: 311: 37.83
+	Hs
		71007 NOTC2_HUMAN (22-2471): 0: 1400: 100.00		ZN724_HUMAN (7-218): 5.5e-88: 282: 12.62
+	Hs
		1047603 NOTC2_HUMAN (22-2471): 0: 1400: 100.00		ZN627_HUMAN (147-419): 1.21e-77: 251: 45.32
+	Hs
		596556 NOTC2_HUMAN (22-2471): 0: 1400: 100.00		ZN823_HUMAN (149-412): 4.28e-66: 224: 50.94
+	Hs
		913717 NOTC2_HUMAN (22-2471): 0: 1400: 100.00		ZN136_HUMAN (165-420): 1.78e-66: 224: 49.81
+	Hs
		1047647 NOTC2_HUMAN (22-2471): 0: 1400: 100.00		ZN555_HUMAN (150-420): 6.47e-65: 222: 47.43
+	Hs
		1047667 NOTC2_HUMAN (22-2471): 0: 1400: 100.00		ZN480_HUMAN (73-302): 3.42e-63: 215: 29.57
+	Hs
		1047764 NOTC2_HUMAN (22-2471): 0: 1400: 100.00		ZN624_HUMAN (2-158): 2.95e-55: 199: 8.18
+	Hs
		1047543 NOTC2_HUMAN (22-2471): 0: 1400: 100.00		ZN235_HUMAN (3-130): 1.62e-41: 159: 6.92
+	Hs
		1047554 NOTC2_HUMAN (22-2471): 0: 1400: 100.00		ZKSC8_HUMAN (357-459): 2.48e-37: 145: 37.50
+	Hs
		510069 NOTC2_HUMAN (22-2471): 0: 1400: 100.00		ZN888_HUMAN (7-131): 3.83e-36: 143: 7.09
+	Hs
		1047779 NOTC2_HUMAN (22-2471): 0: 1400: 100.00		ZN490_HUMAN (98-249): 7.24e-25: 109: 22.37
+	Hs
		1047564 NOTC2_HUMAN (22-2471): 0: 1400: 100.00		ZN791_HUMAN (127-246): 2.71e-23: 104: 24.48
+	Hs
		1047638 NOTC2_HUMAN (22-2471): 0: 1400: 100.00		ZN709_HUMAN (150-303): 1.43e-22: 102: 44.81
+	Hs
		601934 NOTC2_HUMAN (22-2471): 0: 1400: 100.00		ZNF7_HUMAN (90-149): 3.41e-10: 64.3: 37.71
+	Hs
		585113 ANR50_HUMAN (1627-2464): 5.06e-117: 410: 14.38		ZN250_HUMAN (40-156): 1.07e-18: 90.5: 11.77