HitPredict

Interactor 1: HNRPD (Q14103)
Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1)
Gene: HNRNPD

Interactor 2: SMC5 (Q8IY18)
Structural maintenance of chromosomes protein 5 (SMC protein 5) (SMC-5) (hSMC5)
Gene: SMC5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36373674
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0032204 - regulation of telomere maintenance
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 355 Hs			1 1101
+	Hs
		162091 HNRDL_HUMAN (89-355): 3.71e-56: 190: 62.63		SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00
+	Hs
		1221676 ROAA_HUMAN (30-355): 3.41e-55: 185: 53.89		SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00
+	Hs
		852103 ROA3_HUMAN (64-265): 2.66e-50: 174: 37.02		SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00
+	Hs
		1031385 PABP4_HUMAN (88-272): 4.65e-43: 159: 18.52		SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00
+	Hs
		516583 PABP1_HUMAN (88-272): 2.1e-42: 157: 16.93		SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00
+	Hs
		609950 ROA2_HUMAN (98-277): 8.38e-39: 142: 41.40		SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00
+	Hs
		453467 ROA1_HUMAN (63-177): 4.79e-20: 92: 26.83		SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00
+	Hs
		1221731 PABP3_HUMAN (172-267): 5.97e-16: 80.9: 16.50		SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00
+	Hs
		1104162 RA1L2_HUMAN (46-167): 1.11e-13: 72.9: 27.87		SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00
+	Hs
		963547 TIAR_HUMAN (174-269): 2.98e-13: 72.1: 16.50		SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00
+	Hs
		1048192 HNRPD_HUMAN (1-355): 9.1e-72: 229: 100.00		SMC6_HUMAN (9-1069): 7.85e-63: 235: 15.55
+	Sc
		376836 PABP_YEAST (61-266): 4.09e-40: 150: 20.48		SMC3_YEAST (51-1055): 7.78e-71: 260: 13.66
+	Hs
		311478 ROA2_HUMAN (98-277): 8.38e-39: 142: 41.40		SMC2_HUMAN (51-1055): 9.8e-55: 210: 11.41
+	Hs
		522548 HNRPD_HUMAN (1-355): 9.1e-72: 229: 100.00		MYH1_HUMAN (537-989): 5.43e-18: 92.4: 12.25