Protein: GBB3
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 (Transducin beta chain 3)

Gene: GBB3, GNB3
Organism: Homo sapiens
Interactions: 48
UniProt ID: P16520

Gene Ontology (top 5):
GO:0003924 - GTPase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005834 - heterotrimeric G-protein complex
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

597349

GBG2
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2

8

20

Small-scale

0.750

High

597354

GBG5

4

20

Small-scale

0.703

High

597346

GBG10

3

20

Small-scale

0.674

High

418584

GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2

3

20

High-throughput

0.667

High

597375

GBG12

2

20

Small-scale

0.624

High

597352

GBG1
Guanine nucleotide-binding protein G(T) subunit gamma-T1

2

20

Small-scale

0.606

High

597376

CIDEB
Lipid transferase CIDEB

2

1

High-throughput

0.606

High

243464

GBG7

2

20

Small-scale

0.586

High

597345

GBG4

2

20

Small-scale

0.586

High

597353

GBG3

2

20

Small-scale

0.586

High

597359

CUL4A
Cullin-4A

2

20

Small-scale

0.584

High

597340

ARBK1
Beta-adrenergic receptor kinase 1

1

10

Small-scale

0.561

High

597377

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

1

20

Small-scale

0.561

High

597347

ZN131
Zinc finger protein 131

2

2

High-throughput

0.558

High

597351

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

14

High-throughput

0.536

High

597368

CDC5L
Cell division cycle 5-like protein

1

3

High-throughput

0.536

High

597341

CXCR5
C-X-C chemokine receptor type 5

1

2

Small-scale

0.515

High

597360

RCAN2
Calcipressin-2

1

0

High-throughput

0.513

High

597367

RHES
GTP-binding protein Rhes

1

8

Small-scale

0.481

High

158706

GBGT2
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2

1

20

Small-scale

0.479

High

330641

KI20A
Kinesin-like protein KIF20A

1

18

High-throughput

0.479

High

343219

ERR2
Steroid hormone receptor ERR2

1

20

High-throughput

0.479

High

475886

GNAI3
Guanine nucleotide-binding protein G(i) subunit alpha-3

1

20

Small-scale

0.479

High

597338

GBB3
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3

1

16

Small-scale

0.479

High

597342

MTOR
Serine/threonine-protein kinase mTOR

1

8

Small-scale

0.479

High

597343

RGS6
Regulator of G-protein signaling 6

1

13

Small-scale

0.479

High

597344

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

1

20

Small-scale

0.479

High

597348

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

7

High-throughput

0.479

High

597350

GBG11

1

20

Small-scale

0.479

High

597356

GNA12
Guanine nucleotide-binding protein subunit alpha-12

1

20

Small-scale

0.479

High

597358

PHLP
Phosducin-like protein

1

15

Small-scale

0.479

High

597361

KIF14
Kinesin-like protein KIF14

1

7

High-throughput

0.479

High

597363

DDB1
DNA damage-binding protein 1

1

8

Small-scale

0.479

High

597369

CHM4B
Charged multivesicular body protein 4b

1

5

High-throughput

0.479

High

597370

ECT2
Protein ECT2

1

19

High-throughput

0.479

High

597371

NGB
Neuroglobin

1

2

High-throughput

0.479

High

597372

ANLN
Anillin

1

7

High-throughput

0.479

High

597373

RNF12
E3 ubiquitin-protein ligase RLIM

1

7

High-throughput

0.479

High

597374

GBG13

1

6

Small-scale

0.479

High

597357

CD47
Leukocyte surface antigen CD47

1

0

Small-scale

0.458

High

410592

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

16

High-throughput

0.445

High

597339

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

6

Small-scale

0.437

High

597362

EZH2
Histone-lysine N-methyltransferase EZH2

1

15

High-throughput

0.437

High

597366

ESR2
Estrogen receptor beta

1

20

High-throughput

0.407

High

597364

S36A3
Proton-coupled amino acid transporter 3

2

0

High-throughput

0.319

High

597355

CXCL6
C-X-C motif chemokine 6

1

0

High-throughput

0.279

Low

597365

ZN511
Zinc finger protein 511

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025