HitPredict

Interactor 1: HNRPD (Q14103)
Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1)
Gene: HNRNPD

Interactor 2: RALY (Q9UKM9)
RNA-binding protein Raly (Autoantigen p542) (Heterogeneous nuclear ribonucleoprotein C-like 2) (hnRNP core protein C-like 2) (hnRNP associated with lethal yellow protein homolog)
Gene: RALY

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.775

Property	Details
Experiments	22365833, 26318153
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 355 Hs			1 306
+	Mm
		665756 PABP1_MOUSE (88-272): 2.51e-42: 157: 16.93		RALY_MOUSE (1-306): 9.64e-160: 449: 85.58
+	Hs
		162183 HNRDL_HUMAN (89-355): 3.71e-56: 190: 62.63		RALY_HUMAN (1-306): 1.15e-143: 408: 100.00
+	Hs
		516734 PABP1_HUMAN (88-272): 2.1e-42: 157: 16.93		RALY_HUMAN (1-306): 1.15e-143: 408: 100.00
+	Hs
		432703 HNRPD_HUMAN (1-355): 9.1e-72: 229: 100.00		HNRPC_HUMAN (6-219): 3.17e-99: 295: 52.38
+	Hs
		241307 HNRPD_HUMAN (1-355): 9.1e-72: 229: 100.00		HNRC1_HUMAN (6-297): 1.05e-98: 293: 43.43
+	Hs
		453694 ROA1_HUMAN (63-177): 4.79e-20: 92: 26.83		RALY_HUMAN (1-306): 1.15e-143: 408: 100.00
+	Hs
		161936 HNRDL_HUMAN (89-355): 3.71e-56: 190: 62.63		HNRPC_HUMAN (6-219): 3.17e-99: 295: 52.38
+	Hs
		432882 ROAA_HUMAN (30-355): 3.41e-55: 185: 53.89		HNRPC_HUMAN (6-219): 3.17e-99: 295: 52.38
+	Hs
		432615 ROA3_HUMAN (64-265): 2.66e-50: 174: 37.02		HNRPC_HUMAN (6-219): 3.17e-99: 295: 52.38
+	Hs
		432527 PABP1_HUMAN (88-272): 2.1e-42: 157: 16.93		HNRPC_HUMAN (6-219): 3.17e-99: 295: 52.38
+	Hs
		609935 ROA2_HUMAN (98-277): 8.38e-39: 142: 41.40		RALYL_HUMAN (1-224): 3.08e-105: 310: 64.83
+	Hs
		432548 ROA2_HUMAN (98-277): 8.38e-39: 142: 41.40		HNRPC_HUMAN (6-219): 3.17e-99: 295: 52.38
+	Hs
		432514 ROA1_HUMAN (63-177): 4.79e-20: 92: 26.83		HNRPC_HUMAN (6-219): 3.17e-99: 295: 52.38
+	Hs
		71067 ROA1_HUMAN (63-177): 4.79e-20: 92: 26.83		HNRC2_HUMAN (6-218): 4.64e-97: 289: 52.07
+	Hs
		432518 PAB4L_HUMAN (179-259): 1.74e-16: 81.7: 18.29		HNRPC_HUMAN (6-219): 3.17e-99: 295: 52.38
+	Hs
		241260 PAB4L_HUMAN (179-259): 1.74e-16: 81.7: 18.29		HNRC1_HUMAN (6-297): 1.05e-98: 293: 43.43
+	Hs
		201644 MSI1H_HUMAN (21-180): 2.38e-16: 81: 28.13		HNRC1_HUMAN (6-297): 1.05e-98: 293: 43.43
+	Hs
		432745 RA1L2_HUMAN (46-167): 1.11e-13: 72.9: 27.87		HNRPC_HUMAN (6-219): 3.17e-99: 295: 52.38