Protein: APBB3
Amyloid-beta A4 precursor protein-binding family B member 3 (Protein Fe65-like 2) (Fe65L2)

Gene: APBB3
Organism: Homo sapiens
Interactions: 24
UniProt ID: O95704

Gene Ontology (top 5):
GO:0001540 - amyloid-beta binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006355 - regulation of DNA-templated transcription

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

342393

A4
Amyloid-beta precursor protein

9

16

Small-scale

0.973

High

342401

APLP2
Amyloid beta precursor like protein 2

4

15

Small-scale

0.897

High

342398

APLP1
Amyloid beta precursor like protein 1

3

13

Small-scale

0.774

High

342399

CSN2
COP9 signalosome complex subunit 2

2

3

High-throughput

0.628

High

342400

HGFA
Hepatocyte growth factor activator serine protease

2

2

High-throughput

0.628

High

342402

CSN1
COP9 signalosome complex subunit 1

2

2

High-throughput

0.628

High

342405

RBM14
RNA-binding protein 14

2

1

High-throughput

0.628

High

342409

CSN7B
COP9 signalosome complex subunit 7b

2

1

High-throughput

0.628

High

342410

CSN7A
COP9 signalosome complex subunit 7a

2

1

High-throughput

0.628

High

342412

CSN3
COP9 signalosome complex subunit 3

2

3

High-throughput

0.628

High

342411

DAPP1
Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide

2

4

High-throughput

0.628

High

342394

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

2

0

High-throughput

0.602

High

342403

CSN6
COP9 signalosome complex subunit 6

2

0

High-throughput

0.602

High

342404

CSN5
COP9 signalosome complex subunit 5

2

0

High-throughput

0.602

High

342407

CSN4
COP9 signalosome complex subunit 4

2

0

High-throughput

0.602

High

193480

PDPK1
3-phosphoinositide-dependent protein kinase 1

2

2

High-throughput

0.594

High

318551

RHBT1
Rho-related BTB domain-containing protein 1

2

4

High-throughput

0.574

High

342408

RHBT2
Rho-related BTB domain-containing protein 2

2

4

High-throughput

0.574

High

342397

BLK
Tyrosine-protein kinase Blk

1

1

High-throughput

0.536

High

342406

PSMG3
Proteasome assembly chaperone 3

1

0

High-throughput

0.513

High

342391

EGFR
Epidermal growth factor receptor

1

6

High-throughput

0.501

High

342392

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

6

High-throughput

0.501

High

342396

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

0

High-throughput

0.493

High

342395

RAB4A
Ras-related protein Rab-4A

1

4

High-throughput

0.417

High


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Last updated: 11Aug2025