HitPredict

Interactor 1: ELOA1 (Q14241)
Elongin-A (EloA) (Elongin 110 kDa subunit) (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Transcription elongation factor B polypeptide 3)
Gene: ELOA

Interactor 2: ELOC (Q15369)
Elongin-C (EloC) (Elongin 15 kDa subunit) (RNA polymerase II transcription factor SIII subunit C) (SIII p15) (Transcription elongation factor B polypeptide 1)
Gene: ELOC

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.91	0.60	0.739

Property	Details
Experiments	7660129, 10449727, 25878247, 33298525, 18187417, 10692460, 7660122
Identification Methods	pull down, two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II GO:0006367 - transcription initiation at RNA polymerase II promoter GO:0070449 - elongin complex
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 772 Hs			1 112
+	Rn
		949977 ELOA1_RAT (1-772): 2.55e-116: 371: 82.75		ELOC_RAT (1-112): 2.74e-68: 202: 100.00
+	Rn
		949978 Q66HK4_RAT (1-772): 1.64e-116: 371: 82.88		ELOC_RAT (1-112): 2.74e-68: 202: 100.00
+	Hs
		1072250 ELOA2_HUMAN (2-772): 1.58e-85: 288: 45.90		ELOC_HUMAN (1-112): 2.74e-68: 202: 100.00
+	Dm
		1177543 ELOA1_DROME (188-771): 7.08e-28: 121: 24.42		Q7JWD6_DROME (1-112): 1.74e-67: 200: 90.35
+	At
		1323479 Q9SJH8_ARATH (543-754): 2.24e-44: 163: 21.59		Q9FIG0_ARATH (19-110): 1.69e-45: 144: 45.65