HitPredict

Interactor 1: FKBP8 (Q14318)
Peptidyl-prolyl cis-trans isomerase FKBP8 (PPIase FKBP8) (EC 5.2.1.8) (38 kDa FK506-binding protein) (38 kDa FKBP) (FKBP-38) (hFKBP38) (FK506-binding protein 8) (FKBP-8) (FKBPR38) (Rotamase)
Gene: FKBP8

Interactor 2: RPTOR (Q8N122)
Regulatory-associated protein of mTOR (Raptor) (p150 target of rapamycin (TOR)-scaffold protein)
Gene: RPTOR

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	17991864
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 412 Hs			1 1335
+	Hs
		923831 FKB1A_HUMAN (101-204): 1.72e-35: 128: 32.41		RPTOR_HUMAN (1-1335): 0: 1440: 100.00
+	At
		1140062 HSOP2_ARATH (221-392): 5.74e-24: 105: 19.19		RTOR1_ARATH (27-1328): 0: 1169: 40.82
+	At
		1275312 HSOP1_ARATH (221-392): 1.5e-21: 98.8: 16.28		RTOR1_ARATH (27-1328): 0: 1169: 40.82
+	Hs
		1053114 FKBP8_HUMAN (1-412): 5.79e-102: 310: 100.00		FBXW7_HUMAN (961-1324): 5.17e-69: 248: 15.18
+	Hs
		259975 FKBP6_HUMAN (81-380): 6.91e-56: 188: 23.73		TBL1R_HUMAN (1059-1334): 3.26e-59: 215: 12.50
+	Hs
		245547 FKBP6_HUMAN (81-380): 6.91e-56: 188: 23.73		TBL1X_HUMAN (1059-1334): 1.32e-55: 206: 14.24
+	Hs
		863427 FKBP8_HUMAN (1-412): 5.79e-102: 310: 100.00		COPA_HUMAN (1009-1182): 1.34e-10: 68.3: 17.62
+	Hs
		972564 FKBP4_HUMAN (72-404): 6.45e-24: 105: 18.18		FBXW7_HUMAN (961-1324): 5.17e-69: 248: 15.18
+	Hs
		1034955 FKBP5_HUMAN (72-203): 1.44e-18: 89.2: 27.21		FBXW7_HUMAN (961-1324): 5.17e-69: 248: 15.18
+	Hs
		118777 AIP_HUMAN (97-369): 4.45e-54: 184: 18.94		SNR40_HUMAN (1246-1335): 6.58e-16: 82.9: 17.58
+	Sc
		589286 FKBP_YEAST (99-201): 5.31e-33: 121: 32.71		KOG1_YEAST (1087-1332): 1.64e-15: 84.5: 12.36
+	Hs
		972550 FKBP4_HUMAN (72-404): 6.45e-24: 105: 18.18		POC1A_HUMAN (932-1114): 1.11e-17: 89.1: 9.96
+	Hs
		684973 STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00		PI3R4_HUMAN (1102-1335): 7.12e-19: 95.3: 13.78
+	Hs
		684951 STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00		SNR40_HUMAN (1246-1335): 6.58e-16: 82.9: 17.58
+	Hs
		684451 STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00		COPB2_HUMAN (1197-1333): 5.9e-15: 82.2: 15.83
+	Hs
		684552 STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00		COPA_HUMAN (1009-1182): 1.34e-10: 68.3: 17.62