Protein: MTM1
Myotubularin (EC 3.1.3.95) (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (Phosphatidylinositol-3-phosphate phosphatase)

Gene: MTM1
Organism: Homo sapiens
Interactions: 67
UniProt ID: Q13496

Gene Ontology (top 5):
GO:0000045 - autophagosome assembly
GO:0001726 - ruffle
GO:0004438 - phosphatidylinositol-3-phosphate phosphatase activity
GO:0004721 - phosphoprotein phosphatase activity
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

62291

MTMRB
Myotubularin-related protein 11

2

16

High-throughput

0.789

High

1107671

MTMRC
Myotubularin-related protein 12

1

18

Small-scale

0.724

High

1107652

SNX17
Sorting nexin-17

5

3

High-throughput

0.718

High

1107661

TRIMM
Probable E3 ubiquitin-protein ligase TRIML2

2

3

High-throughput

0.628

High

1107648

MTM1
Myotubularin

1

18

High-throughput

0.618

High

1107649

MTMR2
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR2

1

19

High-throughput

0.618

High

1107674

MTMRA
Myotubularin-related protein 10

1

18

High-throughput

0.618

High

520833

HLAC
HLA class I histocompatibility antigen, C alpha chain

2

1

High-throughput

0.611

High

566368

K2C5
Keratin, type II cytoskeletal 5

2

1

High-throughput

0.611

High

777453

K22E
Keratin, type II cytoskeletal 2 epidermal

2

1

High-throughput

0.611

High

606108

DESM
Desmin

1

3

Small-scale

0.604

High

1049263

1433F
14-3-3 protein eta

2

20

High-throughput

0.601

High

255420

SNX2
Sorting nexin-2

2

4

High-throughput

0.584

High

731264

STIP1
Stress-induced-phosphoprotein 1

2

5

High-throughput

0.584

High

138490

BIN1
Myc box-dependent-interacting protein 1

1

4

Small-scale

0.578

High

1107659

MIC60
MICOS complex subunit MIC60

2

0

High-throughput

0.559

High

1107677

STML2
Stomatin-like protein 2, mitochondrial

2

0

High-throughput

0.559

High

62948

POTEF
POTE ankyrin domain family member F

1

2

High-throughput

0.536

High

1107655

RCN1
Reticulocalbin-1

2

1

High-throughput

0.533

High

1107650

BTG3
Protein BTG3

1

0

High-throughput

0.518

High

848997

PTN9
Tyrosine-protein phosphatase non-receptor type 9

1

0

High-throughput

0.513

High

1107663

KBTB7
Kelch repeat and BTB domain-containing protein 7

1

0

High-throughput

0.513

High

1041513

KMT2A
Histone-lysine N-methyltransferase 2A

1

3

Small-scale

0.501

High

377111

GLHA
Glycoprotein hormones alpha chain

1

1

High-throughput

0.489

High

127952

PSD11
26S proteasome non-ATPase regulatory subunit 11

1

1

High-throughput

0.479

High

217264

ARK72
Aflatoxin B1 aldehyde reductase member 2

1

1

High-throughput

0.479

High

229708

CALU
Calumenin

1

2

High-throughput

0.479

High

302827

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

4

High-throughput

0.479

High

325822

UBR5
E3 ubiquitin-protein ligase UBR5

1

4

High-throughput

0.479

High

375491

RASK
GTPase KRas

1

13

High-throughput

0.479

High

532567

CH60
60 kDa heat shock protein, mitochondrial

1

6

High-throughput

0.479

High

773871

SOAT1
Sterol O-acyltransferase 1

1

3

High-throughput

0.479

High

875946

TCPE
T-complex protein 1 subunit epsilon

1

4

High-throughput

0.479

High

934568

TERA
Transitional endoplasmic reticulum ATPase

1

2

High-throughput

0.479

High

1107654

PCM1
Pericentriolar material 1 protein

1

1

High-throughput

0.479

High

1107657

TRBP2
RISC-loading complex subunit TARBP2

1

1

High-throughput

0.479

High

1107660

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.479

High

1107665

EXOC4
Exocyst complex component 4

1

1

Small-scale

0.479

High

1107666

TMX3
Protein disulfide-isomerase TMX3

1

2

High-throughput

0.479

High

1107667

SNX27
Sorting nexin-27

1

8

High-throughput

0.479

High

1107669

TCPH
T-complex protein 1 subunit eta

1

4

High-throughput

0.479

High

1107670

SGIP1
SH3-containing GRB2-like protein 3-interacting protein 1

1

1

High-throughput

0.479

High

1107676

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

1107679

SNX6
Sorting nexin-6

1

4

High-throughput

0.479

High

175030

SC16A
Protein transport protein Sec16A

1

0

High-throughput

0.458

High

176670

PUR4
Phosphoribosylformylglycinamidine synthase

1

0

High-throughput

0.458

High

906514

PSMD7
26S proteasome non-ATPase regulatory subunit 7

1

0

High-throughput

0.458

High

963288

PFD3
Prefoldin subunit 3

1

0

High-throughput

0.458

High

1095525

LIPA1
Liprin-alpha-1

1

0

High-throughput

0.458

High

1104386

ILK
Scaffold protein ILK

1

0

High-throughput

0.458

High

1107651

GANAB
Neutral alpha-glucosidase AB

1

0

High-throughput

0.458

High

1107656

MTFR1
Mitochondrial fission regulator 1

1

0

High-throughput

0.458

High

1107668

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

0

High-throughput

0.458

High

1107672

OSBL3
Oxysterol-binding protein-related protein 3

1

0

High-throughput

0.458

High

1107680

SAM50
Sorting and assembly machinery component 50 homolog

1

0

High-throughput

0.458

High

1052986

VMAT2
Synaptic vesicular amine transporter

1

2

High-throughput

0.445

High

228817

SCO2
Protein SCO2 homolog, mitochondrial

1

4

High-throughput

0.437

High

296235

SCO1
Protein SCO1 homolog, mitochondrial

1

4

High-throughput

0.437

High

1107662

ZN548
Zinc finger protein 548

1

1

High-throughput

0.437

High

1107664

EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1

1

1

High-throughput

0.437

High

1107678

HECD1
E3 ubiquitin-protein ligase HECTD1

1

2

High-throughput

0.437

High

1107675

RELCH
RAB11-binding protein RELCH

2

0

High-throughput

0.318

High

124330

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.249

Low

1107653

OXA1L
Mitochondrial inner membrane protein OXA1L

1

0

High-throughput

0.249

Low

1107658

NDUA9
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial

1

0

High-throughput

0.249

Low

1107673

MIC19
MICOS complex subunit MIC19

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025