HitPredict

Interactor 1: FKBP8 (Q14318)
Peptidyl-prolyl cis-trans isomerase FKBP8 (PPIase FKBP8) (EC 5.2.1.8) (38 kDa FK506-binding protein) (38 kDa FKBP) (FKBP-38) (hFKBP38) (FK506-binding protein 8) (FKBP-8) (FKBPR38) (Rotamase)
Gene: FKBP8

Interactor 2: RPAP3 (Q9H6T3)
RNA polymerase II-associated protein 3
Gene: RPAP3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	TPR_1~TPR_2, TPR_16~TPR_2, TPR_2~TPR_8
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 412 Hs			1 665
+	Hs
		685029 STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00		RPAP3_HUMAN (1-665): 1.27e-121: 378: 100.00
+	Hs
		1034998 FKBP5_HUMAN (72-203): 1.44e-18: 89.2: 27.21		RPAP3_HUMAN (1-665): 1.27e-121: 378: 100.00
+	Hs
		174884 FKBP8_HUMAN (1-412): 5.79e-102: 310: 100.00		OGT1_HUMAN (202-656): 7.67e-29: 125: 11.89
+	Hs
		684718 FKBP8_HUMAN (1-412): 5.79e-102: 310: 100.00		STIP1_HUMAN (100-594): 6.38e-20: 95.9: 14.23
+	Hs
		118697 AIP_HUMAN (97-369): 4.45e-54: 184: 18.94		STIP1_HUMAN (100-594): 6.38e-20: 95.9: 14.23
+	Dm
		817472 FKB12_DROME (107-204): 8.02e-34: 123: 33.33		Q9VPN5_DROME (2-272): 3.38e-31: 129: 21.82
+	Hs
		1012412 Q0VDC6_HUMAN (101-204): 3.56e-34: 125: 32.41		TMTC1_HUMAN (260-662): 3.04e-26: 116: 12.75
+	Hs
		174814 FKBP4_HUMAN (72-404): 6.45e-24: 105: 18.18		OGT1_HUMAN (202-656): 7.67e-29: 125: 11.89
+	Hs
		174661 STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00		OGT1_HUMAN (202-656): 7.67e-29: 125: 11.89
+	Hs
		174855 FKBP5_HUMAN (72-203): 1.44e-18: 89.2: 27.21		OGT1_HUMAN (202-656): 7.67e-29: 125: 11.89
+	Hs
		684646 FKBP4_HUMAN (72-404): 6.45e-24: 105: 18.18		STIP1_HUMAN (100-594): 6.38e-20: 95.9: 14.23
+	Hs
		684432 STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00		STIP1_HUMAN (100-594): 6.38e-20: 95.9: 14.23
+	Sc
		549696 STI1_YEAST (221-371): 6.12e-25: 108: 19.21		STI1_YEAST (65-413): 5.16e-14: 77.2: 16.12
+	Hs
		684691 FKBP5_HUMAN (72-203): 1.44e-18: 89.2: 27.21		STIP1_HUMAN (100-594): 6.38e-20: 95.9: 14.23
+	Hs
		684975 STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00		DNJC7_HUMAN (42-289): 2.69e-15: 81.2: 16.11
+	Hs
		684549 STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00		PPP5_HUMAN (131-251): 3.46e-14: 77.4: 32.23
+	Hs
		297056 FKBP5_HUMAN (72-203): 1.44e-18: 89.2: 27.21		TOM70_HUMAN (36-379): 1.61e-15: 82.2: 16.52
+	Hs
		858619 FKBP5_HUMAN (72-203): 1.44e-18: 89.2: 27.21		PPP5_HUMAN (131-251): 3.46e-14: 77.4: 32.23
+	Hs
		213490 STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00		SGTA_HUMAN (232-399): 1.71e-12: 70.9: 33.33
+	Hs
		684824 STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00		CTR9_HUMAN (203-663): 7.24e-09: 61.2: 9.07