HitPredict

Interactor 1: MYPC2 (Q14324)
Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform)
Gene: MYBPC2

Interactor 2: AMOT (Q4VCS5)
Angiomotin
Gene: AMOT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	23414517
Identification Methods	two hybrid, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1141 Hs			1 1084
+	Hs
		528411 MYPC2_HUMAN (1-1141): 0: 688: 100.00		MYH8_HUMAN (382-687): 3.82e-13: 76.4: 13.10
+	Mm
		250933 MYPC3_MOUSE (9-1141): 0: 654: 49.59		MYH6_MOUSE (273-668): 3.18e-15: 83.1: 10.35
+	Hs
		1118960 MYOM3_HUMAN (566-914): 6.49e-21: 101: 23.91		AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00
+	Hs
		962507 MYPC1_HUMAN (193-441): 5.09e-13: 76: 11.27		AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00
+	Hs
		1119008 TITIN_HUMAN (1007-1139): 1.39e-11: 71.8: 23.31		AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00
+	Hs
		1018317 CNTN1_HUMAN (3-727): 3.48e-34: 144: 9.88		MYH4_HUMAN (350-812): 1.95e-39: 162: 15.92
+	Hs
		234597 DSCAM_HUMAN (460-1140): 4.36e-45: 180: 12.85		AMOL2_HUMAN (296-902): 3.42e-27: 121: 39.81
+	Hs
		148187 DSCAM_HUMAN (460-1140): 4.36e-45: 180: 12.85		CTRO_HUMAN (533-815): 3.66e-12: 73.4: 12.37
+	Hs
		522615 MYPC3_HUMAN (1-639): 2.74e-35: 148: 12.23		MYH7_HUMAN (250-667): 1.32e-15: 84.6: 9.81
+	Hs
		255606 OBSL1_HUMAN (271-435): 2.57e-09: 63.9: 25.90		SMCA4_HUMAN (46-592): 7.62e-32: 137: 12.59
+	Hs
		522597 MYOM2_HUMAN (77-540): 1.74e-20: 100: 15.08		MYH7_HUMAN (250-667): 1.32e-15: 84.6: 9.81
+	Hs
		148575 MYOM2_HUMAN (77-540): 1.74e-20: 100: 15.08		CTRO_HUMAN (533-815): 3.66e-12: 73.4: 12.37
+	Hs
		254437 PTPRF_HUMAN (1045-1139): 6.41e-14: 79.2: 27.55		ROCK2_HUMAN (363-853): 6.63e-18: 91.8: 13.17
+	Hs
		1032039 PTPRS_HUMAN (503-867): 1.21e-14: 81.5: 12.01		RRBP1_HUMAN (179-773): 3.57e-12: 73: 12.40
+	Hs
		724846 MYLK_HUMAN (246-626): 2.95e-09: 63.9: 22.80		MYH9_HUMAN (51-655): 1.51e-14: 81.1: 9.31
+	Ce
		136787 UNC89_CAEEL (51-260): 1.05e-10: 68.7: 11.11		MYSP_CAEEL (402-767): 4.16e-11: 69.2: 20.43
+	Hs
		148199 OBSL1_HUMAN (271-435): 2.57e-09: 63.9: 25.90		CTRO_HUMAN (533-815): 3.66e-12: 73.4: 12.37
+	Hs
		1051385 TITIN_HUMAN (1007-1139): 1.39e-11: 71.8: 23.31		DCTN1_HUMAN (510-863): 3.81e-09: 63.3: 14.85
+	Hs
		255878 OBSL1_HUMAN (271-435): 2.57e-09: 63.9: 25.90		SRCAP_HUMAN (828-1033): 1.6e-09: 64.6: 21.40
+	Hs
		256185 OBSL1_HUMAN (271-435): 2.57e-09: 63.9: 25.90		PCLO_HUMAN (834-1051): 2.15e-09: 64.2: 18.30