Protein: EPC2
Enhancer of polycomb homolog 2 (EPC-like)

Gene: EPC2
Organism: Homo sapiens
Interactions: 58
UniProt ID: Q52LR7

Gene Ontology (top 5):
GO:0000786 - nucleosome
GO:0005634 - nucleus
GO:0006281 - DNA repair
GO:0006325 - chromatin organization
GO:0006357 - regulation of transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1198106

KAT5
Histone acetyltransferase KAT5

6

7

Small-scale

0.947

High

1198120

ING3
Inhibitor of growth protein 3

3

5

Small-scale

0.861

High

1198121

MO4L1
Mortality factor 4-like protein 1

7

5

Small-scale

0.742

High

1136787

MO4L2
Mortality factor 4-like protein 2

6

5

Small-scale

0.729

High

1198124

RUVB2
RuvB-like 2

5

6

High-throughput

0.714

High

1198119

MRGBP
MRG/MORF4L-binding protein

5

1

Small-scale

0.709

High

340336

YETS4
YEATS domain-containing protein 4

4

3

High-throughput

0.699

High

1198097

FOXR1
Forkhead box protein R1

4

3

High-throughput

0.699

High

1198125

RUVB1
RuvB-like 1

4

6

High-throughput

0.697

High

1198104

ING5
Inhibitor of growth protein 5

1

5

High-throughput

0.691

High

1198107

H2B1A
Histone H2B type 1-A

4

7

High-throughput

0.691

High

372199

MYC
Myc proto-oncogene protein

4

7

High-throughput

0.676

High

1198126

TRRAP
Transformation/transcription domain-associated protein

3

3

High-throughput

0.675

High

1053295

MBTD1
MBT domain-containing protein 1

3

1

Small-scale

0.667

High

1198098

FOXR2
Forkhead box protein R2

3

3

High-throughput

0.667

High

502010

H2AZ
Histone H2A.Z

3

2

Small-scale

0.662

High

1198115

EAF6
Chromatin modification-related protein MEAF6

3

2

High-throughput

0.662

High

1198100

JAZF1
Juxtaposed with another zinc finger protein 1

3

2

Small-scale

0.656

High

553750

MYCL
Protein L-Myc

2

7

High-throughput

0.628

High

959595

MAX
Protein max

2

7

Small-scale

0.611

High

1198108

EP400
E1A-binding protein p400

2

3

Small-scale

0.611

High

1198114

BRD8
Bromodomain-containing protein 8

2

3

High-throughput

0.611

High

1198118

DMAP1
DNA methyltransferase 1-associated protein 1

2

7

High-throughput

0.611

High

1198116

PLAC1
Placenta-specific protein 1

3

1

High-throughput

0.609

High

911262

IMA5
Importin subunit alpha-5

2

1

High-throughput

0.601

High

1155293

VPS72
Vacuolar protein sorting-associated protein 72 homolog

2

1

Small-scale

0.601

High

833740

KDM5C
Lysine-specific demethylase 5C

1

2

High-throughput

0.536

High

938734

HNRH2
Heterogeneous nuclear ribonucleoprotein H2

1

1

High-throughput

0.536

High

1162951

H2B2E
Histone H2B type 2-E

1

8

High-throughput

0.536

High

1198101

H2B3B
Histone H2B type 3-B

1

8

High-throughput

0.536

High

650793

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

0

High-throughput

0.513

High

854095

KI67
Proliferation marker protein Ki-67

1

0

High-throughput

0.513

High

1122990

FHL2
Four and a half LIM domains protein 2

1

0

High-throughput

0.513

High

210011

CRX
Cone-rod homeobox protein

1

1

High-throughput

0.479

High

339767

KLF8
Krueppel-like factor 8

1

10

High-throughput

0.479

High

833962

HNF4A
Hepatocyte nuclear factor 4-alpha

1

3

High-throughput

0.479

High

944673

KLF3
Krueppel-like factor 3

1

10

High-throughput

0.479

High

979766

H4
Histone H4

1

2

High-throughput

0.479

High

980813

H2B1C
Histone H2B type 1-C/E/F/G/I

1

8

High-throughput

0.479

High

1198103

SP7
Transcription factor Sp7

1

9

High-throughput

0.479

High

1198105

ESR2
Estrogen receptor beta

1

4

High-throughput

0.479

High

1198111

ELF4
ETS-related transcription factor Elf-4

1

3

High-throughput

0.479

High

1198112

KLF6
Krueppel-like factor 6

1

10

High-throughput

0.479

High

1198122

KLF15
Krueppel-like factor 15

1

10

High-throughput

0.479

High

1198123

MED23
Mediator of RNA polymerase II transcription subunit 23

1

1

High-throughput

0.479

High

886924

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.458

High

995071

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.458

High

1115231

CUL4B
Cullin-4B

1

0

High-throughput

0.458

High

1198099

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1198113

AN32E
Acidic leucine-rich nuclear phosphoprotein 32 family member E

1

1

Small-scale

0.445

High

1198110

CEP63
Centrosomal protein of 63 kDa

1

1

High-throughput

0.417

High

1198102

MOT11
Monocarboxylate transporter 11

1

1

High-throughput

0.407

High

391272

FRIL
Ferritin light chain

1

0

High-throughput

0.279

Low

549604

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

0

High-throughput

0.279

Low

1198109

LURA1
Leucine rich adaptor protein 1

1

0

High-throughput

0.279

Low

1198127

PCDB3
Protocadherin beta-3

1

0

High-throughput

0.279

Low

106052

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

1198117

RAB18
Ras-related protein Rab-18

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025