Protein: MBTD1
MBT domain-containing protein 1

Gene: MBTD1
Organism: Homo sapiens
Interactions: 57
UniProt ID: Q05BQ5

Gene Ontology (top 5):
GO:0000724 - double-strand break repair via homologous recombination
GO:0000786 - nucleosome
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0008270 - zinc ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1053316

MO4L1
Mortality factor 4-like protein 1

8

3

Small-scale

0.748

High

1053290

MO4L2
Mortality factor 4-like protein 2

7

3

Small-scale

0.745

High

1053317

RUVB2
RuvB-like 2

6

3

Small-scale

0.735

High

1053303

KAT5
Histone acetyltransferase KAT5

6

2

Small-scale

0.733

High

1053311

EAF6
Chromatin modification-related protein MEAF6

5

1

Small-scale

0.716

High

1053318

RUVB1
RuvB-like 1

5

3

Small-scale

0.716

High

340320

YETS4
YEATS domain-containing protein 4

6

0

Small-scale

0.705

High

1053296

FOXR1
Forkhead box protein R1

4

3

High-throughput

0.699

High

1053309

BRD8
Bromodomain-containing protein 8

4

2

Small-scale

0.694

High

1053314

MRGBP
MRG/MORF4L-binding protein

5

0

Small-scale

0.688

High

960405

PSME3
Proteasome activator complex subunit 3

3

1

High-throughput

0.667

High

1053295

EPC2
Enhancer of polycomb homolog 2

3

1

Small-scale

0.667

High

1053297

FOXR2
Forkhead box protein R2

3

3

High-throughput

0.667

High

1053304

H2B1A
Histone H2B type 1-A

3

17

High-throughput

0.667

High

501970

H2AZ
Histone H2A.Z

3

5

Small-scale

0.662

High

1053305

EP400
E1A-binding protein p400

3

6

Small-scale

0.656

High

1053320

TRRAP
Transformation/transcription domain-associated protein

3

1

Small-scale

0.656

High

371838

MYC
Myc proto-oncogene protein

3

10

High-throughput

0.640

High

1053310

EPC1
Enhancer of polycomb homolog 1

2

1

Small-scale

0.639

High

1053313

DMAP1
DNA methyltransferase 1-associated protein 1

3

0

Small-scale

0.638

High

1053299

JAZF1
Juxtaposed with another zinc finger protein 1

3

0

Small-scale

0.628

High

1053286

MBTD1
MBT domain-containing protein 1

1

16

Small-scale

0.618

High

355199

ACL6A
Actin-like protein 6A

2

2

Small-scale

0.611

High

952765

ACTB
Actin, cytoplasmic 1

2

2

Small-scale

0.611

High

959569

MAX
Protein max

2

7

Small-scale

0.611

High

1053315

ING3
Inhibitor of growth protein 3

2

2

Small-scale

0.611

High

979543

H4
Histone H4

2

8

Small-scale

0.608

High

1053294

VPS72
Vacuolar protein sorting-associated protein 72 homolog

2

0

Small-scale

0.585

High

944635

KLF3
Krueppel-like factor 3

2

13

High-throughput

0.584

High

553744

MYCL
Protein L-Myc

2

8

High-throughput

0.574

High

833725

KDM5C
Lysine-specific demethylase 5C

1

3

High-throughput

0.536

High

1053289

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

3

High-throughput

0.536

High

1053298

CSN6
COP9 signalosome complex subunit 6

1

1

High-throughput

0.536

High

1053300

H2B3B
Histone H2B type 3-B

1

17

High-throughput

0.536

High

1053301

ING5
Inhibitor of growth protein 5

1

2

High-throughput

0.536

High

279347

TULP3
Tubby-related protein 3

1

0

High-throughput

0.518

High

1053319

PDIP2
Polymerase delta-interacting protein 2

1

0

High-throughput

0.513

High

142958

NFIB
Nuclear factor 1 B-type

1

9

High-throughput

0.479

High

339725

KLF8
Krueppel-like factor 8

1

12

High-throughput

0.479

High

413684

P53
Cellular tumor antigen p53

1

2

High-throughput

0.479

High

473937

NFIC
Nuclear factor 1 C-type

1

11

High-throughput

0.479

High

738971

ELF1
ETS-related transcription factor Elf-1

1

12

High-throughput

0.479

High

754811

H2B1B
Histone H2B type 1-B

1

17

Small-scale

0.479

High

833921

HNF4A
Hepatocyte nuclear factor 4-alpha

1

7

High-throughput

0.479

High

980712

H2B1C
Histone H2B type 1-C/E/F/G/I

1

17

High-throughput

0.479

High

1053287

NFIA
Nuclear factor 1 A-type

1

9

High-throughput

0.479

High

1053293

ELF2
ETS-related transcription factor Elf-2

1

11

High-throughput

0.479

High

1053302

ESR2
Estrogen receptor beta

1

7

High-throughput

0.479

High

1053306

ELF4
ETS-related transcription factor Elf-4

1

12

High-throughput

0.479

High

1053307

KLF6
Krueppel-like factor 6

1

15

High-throughput

0.479

High

1053308

KLF16
Krueppel-like factor 16

1

13

High-throughput

0.479

High

1053292

SF01
Splicing factor 1

1

0

High-throughput

0.438

High

1053312

PLAC1
Placenta-specific protein 1

3

0

High-throughput

0.347

High

1053288

SRSF9
Serine/arginine-rich splicing factor 9

1

0

High-throughput

0.279

Low

902827

BLK
Tyrosine-protein kinase Blk

1

0

High-throughput

0.269

Low

1053291

PLEC
Plectin

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025