HitPredict

Interactor 1: MYPC2 (Q14324)
Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform)
Gene: MYBPC2

Interactor 2: MYOME (Q5VU43)
Myomegalin (Cardiomyopathy-associated protein 2) (Phosphodiesterase 4D-interacting protein)
Gene: PDE4DIP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.50	0.494

Property	Details
Experiments	23414517
Identification Methods	two hybrid, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1141 Hs			1 2346
+	Hs
		234531 DSCAM_HUMAN (460-1140): 4.36e-45: 180: 12.85		MYOME_HUMAN (1-2346): 0: 703: 100.00
+	Hs
		1060196 MYPC3_HUMAN (1-639): 2.74e-35: 148: 12.23		MYOME_HUMAN (1-2346): 0: 703: 100.00
+	Mm
		250933 MYPC3_MOUSE (9-1141): 0: 654: 49.59		MYH6_MOUSE (1379-2333): 4.13e-28: 127: 9.32
+	Hs
		852390 MYOM1_HUMAN (636-725): 2.01e-09: 64.3: 35.87		MYOME_HUMAN (1-2346): 0: 703: 100.00
+	Hs
		528411 MYPC2_HUMAN (1-1141): 0: 688: 100.00		MYH8_HUMAN (1820-2316): 2.84e-12: 75: 11.75
+	Mm
		250923 MYPC3_MOUSE (9-1141): 0: 654: 49.59		LAMB1_MOUSE (342-655): 3.81e-12: 74.3: 23.55
+	Hs
		1018317 CNTN1_HUMAN (3-727): 3.48e-34: 144: 9.88		MYH4_HUMAN (1279-2334): 2.89e-32: 140: 9.95
+	Hs
		522615 MYPC3_HUMAN (1-639): 2.74e-35: 148: 12.23		MYH7_HUMAN (1-709): 1.93e-23: 111: 10.58
+	Hs
		255785 OBSL1_HUMAN (271-435): 2.57e-09: 63.9: 25.90		GOGB1_HUMAN (880-2332): 2.13e-37: 157: 10.38
+	Hs
		522597 MYOM2_HUMAN (77-540): 1.74e-20: 100: 15.08		MYH7_HUMAN (1-709): 1.93e-23: 111: 10.58
+	Dm
		404245 TITIN_DROME (980-1140): 3.3e-17: 90.3: 20.99		MYSA_DROME (29-785): 1.4e-23: 112: 11.88
+	Hs
		255591 OBSL1_HUMAN (271-435): 2.57e-09: 63.9: 25.90		CENPF_HUMAN (1261-2312): 1.38e-21: 105: 10.69
+	Hs
		724846 MYLK_HUMAN (246-626): 2.95e-09: 63.9: 22.80		MYH9_HUMAN (1753-2327): 1.1e-12: 76.2: 11.23
+	Hs
		551790 TITIN_HUMAN (1007-1139): 1.39e-11: 71.8: 23.31		DESP_HUMAN (6-681): 6.09e-10: 67.4: 20.72
+	Hs
		255442 OBSL1_HUMAN (271-435): 2.57e-09: 63.9: 25.90		LAMB1_HUMAN (342-655): 2.89e-12: 74.7: 24.86
+	Hs
		255483 OBSL1_HUMAN (271-435): 2.57e-09: 63.9: 25.90		DESP_HUMAN (6-681): 6.09e-10: 67.4: 20.72