Protein: LMBL2
Lethal(3)malignant brain tumor-like protein 2 (H-l(3)mbt-like protein 2) (L(3)mbt-like protein 2)

Gene: LMBL2, L3MBTL2
Organism: Homo sapiens
Interactions: 212
UniProt ID: Q969R5

Gene Ontology (top 5):
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0007398 - ectoderm development
GO:0008270 - zinc ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1380947

RING2
E3 ubiquitin-protein ligase RING2

8

20

Small-scale

0.754

High

1380958

PCGF6
Polycomb group RING finger protein 6

7

20

Small-scale

0.751

High

282764

E2F6
Transcription factor E2F6

7

10

Small-scale

0.747

High

1326022

RYBP
RING1 and YY1-binding protein

7

4

High-throughput

0.747

High

959630

MAX
Protein max

6

7

Small-scale

0.736

High

965142

WDR5
WD repeat-containing protein 5

6

1

High-throughput

0.735

High

1314034

YAF2
YY1-associated factor 2

6

4

High-throughput

0.732

High

1097467

CBX3
Chromobox protein homolog 3

5

18

Small-scale

0.724

High

1122853

TFDP1
Transcription factor Dp-1

5

3

High-throughput

0.720

High

1109966

HDAC1
Histone deacetylase 1

5

10

High-throughput

0.716

High

1356498

PHF10
PHD finger protein 10

4

11

High-throughput

0.705

High

1055838

RING1
E3 ubiquitin-protein ligase RING1

4

20

High-throughput

0.704

High

1310100

MGAP
MAX gene-associated protein

4

3

High-throughput

0.704

High

1380969

EAF6
Chromatin modification-related protein MEAF6

4

1

High-throughput

0.700

High

1236066

LIN54
Protein lin-54 homolog

4

2

High-throughput

0.697

High

1122890

TFDP2
Transcription factor Dp-2

3

3

High-throughput

0.675

High

1368035

HDAC2
Histone deacetylase 2

3

10

High-throughput

0.675

High

610429

PRS6A
26S proteasome regulatory subunit 6A

3

7

High-throughput

0.667

High

960514

PSME3
Proteasome activator complex subunit 3

3

1

High-throughput

0.667

High

1324705

MIER2
Mesoderm induction early response protein 2

3

14

High-throughput

0.667

High

787829

PEDF
Pigment epithelium-derived factor

3

2

High-throughput

0.662

High

1380960

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

3

1

High-throughput

0.662

High

980099

H4
Histone H4

4

8

Small-scale

0.659

High

1380944

STAC3
SH3 and cysteine-rich domain-containing protein 3

2

1

High-throughput

0.646

High

372771

MYC
Myc proto-oncogene protein

3

10

High-throughput

0.640

High

296543

STAM2
Signal transducing adapter molecule 2

3

0

High-throughput

0.639

High

465068

ZFY
Zinc finger Y-chromosomal protein

3

0

High-throughput

0.639

High

1380993

CIZ1
Cip1-interacting zinc finger protein

3

0

High-throughput

0.634

High

316939

MTA2
Metastasis-associated protein MTA2

2

14

High-throughput

0.628

High

352215

MBD3
Methyl-CpG-binding domain protein 3

2

1

High-throughput

0.628

High

1014175

CBX1
Chromobox protein homolog 1

2

20

High-throughput

0.628

High

1102619

MTA1
Metastasis-associated protein MTA1

2

14

High-throughput

0.628

High

1128446

ITPR3
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3

2

1

High-throughput

0.628

High

1357120

ZN296
Zinc finger protein 296

2

2

High-throughput

0.628

High

1061804

TLE5
TLE family member 5

2

0

High-throughput

0.623

High

269330

HSF2B
Heat shock factor 2-binding protein

2

2

High-throughput

0.606

High

893724

MEOX1
Homeobox protein MOX-1

2

1

High-throughput

0.606

High

1007970

PO6F2
POU domain, class 6, transcription factor 2

2

2

High-throughput

0.606

High

1048951

REL
Proto-oncogene c-Rel

2

2

High-throughput

0.606

High

1160983

NRF1
Nuclear respiratory factor 1

2

1

High-throughput

0.606

High

1281435

ZN467
Zinc finger protein 467

2

1

High-throughput

0.606

High

1290923

TAXB1
Tax1-binding protein 1

2

1

High-throughput

0.606

High

1380971

ZBT26
Zinc finger and BTB domain-containing protein 26

2

5

High-throughput

0.606

High

1380977

THAP1
THAP domain-containing protein 1

2

1

High-throughput

0.606

High

702145

ITPI2
Protein ITPRID2

2

0

High-throughput

0.602

High

1358816

KBTB7
Kelch repeat and BTB domain-containing protein 7

2

0

High-throughput

0.602

High

188334

HDAC3
Histone deacetylase 3

1

10

Small-scale

0.594

High

474187

NFIC
Nuclear factor 1 C-type

2

11

High-throughput

0.584

High

1054761

SUH
Recombining binding protein suppressor of hairless

2

4

High-throughput

0.584

High

1133586

NFIX
Nuclear factor 1 X-type

2

9

High-throughput

0.584

High

517683

ZBT48
Zinc finger and BTB domain-containing protein 48

2

0

High-throughput

0.580

High

1185831

ZN829
Zinc finger protein 829

2

0

High-throughput

0.580

High

1244629

GASP3
G protein-coupled receptor associated sorting protein 3

2

0

High-throughput

0.580

High

1288064

BIVM
Basic immunoglobulin-like variable motif-containing protein

2

0

High-throughput

0.580

High

1294322

TRI50
E3 ubiquitin-protein ligase TRIM50

2

0

High-throughput

0.580

High

1380936

TEKT1
Tektin-1

2

0

High-throughput

0.580

High

1380956

CC106
Coiled-coil domain-containing protein 106

2

0

High-throughput

0.580

High

1380973

4ET
Eukaryotic translation initiation factor 4E transporter

2

0

High-throughput

0.580

High

1380976

F217B
Protein FAM217B

2

0

High-throughput

0.580

High

1380979

RBAK
RB-associated KRAB zinc finger protein

2

0

High-throughput

0.580

High

1380995

SSUH2
Protein SSUH2 homolog

2

0

High-throughput

0.580

High

1226412

TBC9B
TBC1 domain family member 9B

2

2

High-throughput

0.578

High

1380996

LMBL1
Lethal(3)malignant brain tumor-like protein 1

1

15

High-throughput

0.575

High

1128357

ITPR2
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2

2

1

High-throughput

0.574

High

1380978

ASB6
Ankyrin repeat and SOCS box protein 6

2

1

High-throughput

0.574

High

1311451

TRI42
Tripartite motif-containing protein 42

1

2

High-throughput

0.573

High

998647

H31
Histone H3.1

2

13

Small-scale

0.563

High

1325744

LNX2
Ligand of Numb protein X 2

1

1

High-throughput

0.560

High

1380963

CAD19
Cadherin-19

2

1

High-throughput

0.558

High

353724

DRC4
Dynein regulatory complex subunit 4

2

1

High-throughput

0.553

High

1380994

AMOL2
Angiomotin-like protein 2

2

2

High-throughput

0.553

High

216506

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

5

High-throughput

0.536

High

724614

S10A7
Protein S100-A7

1

4

High-throughput

0.536

High

899514

TCPD
T-complex protein 1 subunit delta

1

3

High-throughput

0.536

High

920867

ACLY
ATP-citrate synthase

1

1

High-throughput

0.536

High

1004932

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.536

High

1244929

FOXR1
Forkhead box protein R1

1

3

High-throughput

0.536

High

1324578

PIAS4
E3 SUMO-protein ligase PIAS4

1

1

High-throughput

0.536

High

1360985

P66B
Transcriptional repressor p66-beta

1

2

High-throughput

0.536

High

1380937

TRI52
E3 ubiquitin-protein ligase TRIM52

1

1

High-throughput

0.536

High

1380942

CHAP1
Chromosome alignment-maintaining phosphoprotein 1

1

1

High-throughput

0.536

High

1380972

KMT5A
N-lysine methyltransferase KMT5A

1

9

High-throughput

0.536

High

1232781

Q6FI91
TSPYL protein

1

2

High-throughput

0.515

High

284857

TADA3
Transcriptional adapter 3

1

0

High-throughput

0.513

High

1099750

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

0

High-throughput

0.513

High

1128660

ZN460
Zinc finger protein 460

1

0

High-throughput

0.513

High

1156314

HSPB2
Heat shock protein beta-2

1

0

High-throughput

0.513

High

1380946

PFD5
Prefoldin subunit 5

1

0

High-throughput

0.513

High

1380961

COMD4
COMM domain-containing protein 4

1

0

High-throughput

0.513

High

1380981

FOXJ2
Forkhead box protein J2

1

0

High-throughput

0.513

High

1380990

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.513

High

1380999

MOFA1
MORF4 family-associated protein 1

1

0

High-throughput

0.513

High

297668

PIAS1
E3 SUMO-protein ligase PIAS1

1

1

Small-scale

0.501

High

610814

TCPA
T-complex protein 1 subunit alpha

1

3

High-throughput

0.489

High

649749

SPR1B
Cornifin-B

1

1

High-throughput

0.489

High

821492

TCPZ
T-complex protein 1 subunit zeta

1

3

High-throughput

0.489

High

876104

TCPE
T-complex protein 1 subunit epsilon

1

4

High-throughput

0.489

High

882077

TCPG
T-complex protein 1 subunit gamma

1

4

High-throughput

0.489

High

899168

TCPQ
T-complex protein 1 subunit theta

1

6

High-throughput

0.489

High

1007188

TCPB
T-complex protein 1 subunit beta

1

4

High-throughput

0.489

High

1208318

SPXN2
Sperm protein associated with the nucleus on the X chromosome N2

1

2

High-throughput

0.489

High

1380952

TCPH
T-complex protein 1 subunit eta

1

4

High-throughput

0.489

High

1380962

TSYL1
Testis-specific Y-encoded-like protein 1

1

2

High-throughput

0.481

High

143174

NFIB
Nuclear factor 1 B-type

1

9

High-throughput

0.479

High

143462

E2F3
Transcription factor E2F3

1

10

Small-scale

0.479

High

173176

XPO1
Exportin-1

1

2

High-throughput

0.479

High

210082

CRX
Cone-rod homeobox protein

1

7

High-throughput

0.479

High

225076

TLX3
T-cell leukemia homeobox protein 3

1

1

High-throughput

0.479

High

259022

DNJA2
DnaJ homolog subfamily A member 2

1

4

High-throughput

0.479

High

298944

DNJB5
DnaJ homolog subfamily B member 5

1

4

High-throughput

0.479

High

339820

KLF8
Krueppel-like factor 8

1

12

High-throughput

0.479

High

349189

LATS1
Serine/threonine-protein kinase LATS1

1

1

High-throughput

0.479

High

442784

RB
Retinoblastoma-associated protein

1

2

Small-scale

0.479

High

664787

CCND1
G1/S-specific cyclin-D1

1

2

High-throughput

0.479

High

675616

TYY1
Transcriptional repressor protein YY1

1

7

High-throughput

0.479

High

679228

DNJB1
DnaJ homolog subfamily B member 1

1

4

High-throughput

0.479

High

739015

ELF1
ETS-related transcription factor Elf-1

1

12

High-throughput

0.479

High

765775

BMI1
Polycomb complex protein BMI-1

1

20

High-throughput

0.479

High

766109

PCGF2
Polycomb group RING finger protein 2

1

20

High-throughput

0.479

High

832554

ETV3
ETS translocation variant 3

1

10

High-throughput

0.479

High

834019

HNF4A
Hepatocyte nuclear factor 4-alpha

1

7

High-throughput

0.479

High

837075

ELK3
ETS domain-containing protein Elk-3

1

12

High-throughput

0.479

High

877542

LHX1
LIM/homeobox protein Lhx1

1

4

High-throughput

0.479

High

895772

LHX2
LIM/homeobox protein Lhx2

1

5

High-throughput

0.479

High

944718

KLF3
Krueppel-like factor 3

1

13

High-throughput

0.479

High

1006866

PHC1
Polyhomeotic-like protein 1

1

16

High-throughput

0.479

High

1017088

H33
Histone H3.3

1

13

High-throughput

0.479

High

1037877

HEN1
Helix-loop-helix protein 1

1

1

High-throughput

0.479

High

1050745

MAD1
Max dimerization protein 1

1

8

Small-scale

0.479

High

1087923

NFIA
Nuclear factor 1 A-type

1

9

High-throughput

0.479

High

1146254

ZMY11
Zinc finger MYND domain-containing protein 11

1

3

Small-scale

0.479

High

1152722

ELF2
ETS-related transcription factor Elf-2

1

11

High-throughput

0.479

High

1161986

H31T
Histone H3.1t

1

13

Small-scale

0.479

High

1185934

PCGF3
Polycomb group RING finger protein 3

1

20

High-throughput

0.479

High

1204627

BCORL
BCL-6 corepressor-like protein 1

1

4

High-throughput

0.479

High

1250630

BCOR
BCL-6 corepressor

1

9

High-throughput

0.479

High

1276597

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.479

High

1277201

POGZ
Pogo transposable element with ZNF domain

1

2

High-throughput

0.479

High

1280300

DNJB7
DnaJ homolog subfamily B member 7

1

5

High-throughput

0.479

High

1286252

PCGF5
Polycomb group RING finger protein 5

1

20

High-throughput

0.479

High

1289514

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.479

High

1326291

NIN
Ninein

1

2

High-throughput

0.479

High

1338883

NUP43
Nucleoporin Nup43

1

4

High-throughput

0.479

High

1340146

KDM2B
Lysine-specific demethylase 2B

1

1

High-throughput

0.479

High

1364499

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

1

Small-scale

0.479

High

1368554

KAT6A
Histone acetyltransferase KAT6A

1

5

High-throughput

0.479

High

1379926

LHX4
LIM/homeobox protein Lhx4

1

5

High-throughput

0.479

High

1380939

PF21A
PHD finger protein 21A

1

10

High-throughput

0.479

High

1380945

CIC
Protein capicua homolog

1

4

High-throughput

0.479

High

1380948

FEV
Protein FEV

1

10

High-throughput

0.479

High

1380949

ELF4
ETS-related transcription factor Elf-4

1

12

High-throughput

0.479

High

1380950

DNJC7
DnaJ homolog subfamily C member 7

1

2

High-throughput

0.479

High

1380953

ANM1
Protein arginine N-methyltransferase 1

1

1

High-throughput

0.479

High

1380955

PCGF1
Polycomb group RING finger protein 1

1

20

High-throughput

0.479

High

1380957

KLF16
Krueppel-like factor 16

1

13

High-throughput

0.479

High

1380967

SMRCD
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1

1

5

High-throughput

0.479

High

1380984

RERE
Arginine-glutamic acid dipeptide repeats protein

1

12

High-throughput

0.479

High

1380986

LHX3
LIM/homeobox protein Lhx3

1

5

High-throughput

0.479

High

1380987

ZMYM2
Zinc finger MYM-type protein 2

1

2

High-throughput

0.479

High

1380988

DNJB4
DnaJ homolog subfamily B member 4

1

4

High-throughput

0.479

High

1380991

KLF15
Krueppel-like factor 15

1

16

High-throughput

0.479

High

1380992

RCOR1
REST corepressor 1

1

14

High-throughput

0.479

High

1380998

KLF12
Krueppel-like factor 12

1

12

High-throughput

0.479

High

1380966

DNJC5
DnaJ homolog subfamily C member 5

1

4

High-throughput

0.470

High

51131

A1L3A9
TBC1 domain family member 9B

1

2

High-throughput

0.470

High

1380940

THA11
THAP domain-containing protein 11

1

0

High-throughput

0.460

High

519411

MYB
Transcriptional activator Myb

1

0

High-throughput

0.458

High

533964

IRF1
Interferon regulatory factor 1

1

0

High-throughput

0.458

High

621705

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

688293

TTP
mRNA decay activator protein ZFP36

1

0

High-throughput

0.458

High

1119594

NFYC
Nuclear transcription factor Y subunit gamma

1

0

High-throughput

0.458

High

1140659

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1212434

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.458

High

1276088

KANL1
KAT8 regulatory NSL complex subunit 1

1

0

High-throughput

0.458

High

1380965

ADNP
Activity-dependent neuroprotector homeobox protein

1

0

High-throughput

0.458

High

1380968

KANL2
KAT8 regulatory NSL complex subunit 2

1

0

High-throughput

0.458

High

1380982

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

0

High-throughput

0.458

High

1380983

KANL3
KAT8 regulatory NSL complex subunit 3

1

0

High-throughput

0.458

High

1380989

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1380997

LOXL2
Lysyl oxidase homolog 2

1

0

High-throughput

0.458

High

1380980

GRHL1
Grainyhead-like protein 1 homolog

1

2

High-throughput

0.445

High

1380975

ZF64B
Zinc finger protein 64

1

0

High-throughput

0.438

High

1380959

RHBT2
Rho-related BTB domain-containing protein 2

1

3

High-throughput

0.437

High

1380970

FBRS
Probable fibrosin-1

1

1

High-throughput

0.437

High

1017462

FOXK1
Forkhead box protein K1

1

0

High-throughput

0.426

High

640251

EPHA1
Ephrin type-A receptor 1

1

1

High-throughput

0.417

High

1380943

Q96KY9
CDH19 protein

1

1

High-throughput

0.407

High

1330669

BEND7
BEN domain-containing protein 7

3

0

High-throughput

0.348

High

646908

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

2

0

High-throughput

0.337

High

619259

TNNI1
Troponin I, slow skeletal muscle

2

0

High-throughput

0.316

High

725433

KAP1
cAMP-dependent protein kinase type I-beta regulatory subunit

2

0

High-throughput

0.316

High

1063499

GOGA2
Golgin subfamily A member 2

2

0

High-throughput

0.316

High

1206416

EFHC2
EF-hand domain-containing family member C2

2

0

High-throughput

0.316

High

1217445

GKAP1
G kinase-anchoring protein 1

2

0

High-throughput

0.316

High

1347434

CEP76
Centrosomal protein of 76 kDa

2

0

High-throughput

0.316

High

1380964

CARD9
Caspase recruitment domain-containing protein 9

2

0

High-throughput

0.316

High

1380974

PICK1
PRKCA-binding protein

2

0

High-throughput

0.316

High

1103517

MPP3
MAGUK p55 subfamily member 3

1

0

High-throughput

0.282

High

391390

FRIL
Ferritin light chain

1

0

High-throughput

0.279

Low

399608

VTNC
Vitronectin

1

0

High-throughput

0.279

Low

1258659

IKIP
Inhibitor of nuclear factor kappa-B kinase-interacting protein

1

0

High-throughput

0.279

Low

1323700

CRBG2
Beta/gamma crystallin domain-containing protein 2

1

0

High-throughput

0.279

Low

1380941

MYO19
Unconventional myosin-XIX

1

0

High-throughput

0.279

Low

1380954

DHB14
L-fucose dehydrogenase

1

0

High-throughput

0.279

Low

1380985

ATX10
Ataxin-10

1

0

High-throughput

0.279

Low

1328381

CCD33
Coiled-coil domain-containing protein 33

1

0

High-throughput

0.251

Low

1135030

CUL7
Cullin-7

1

0

High-throughput

0.249

Low

1380938

VP33A
Vacuolar protein sorting-associated protein 33A

1

0

High-throughput

0.249

Low

58892

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

0

High-throughput

0.232

Low

87518

OSCRI
SCRIB overlapping open reading frame protein

1

0

High-throughput

0.232

Low

216324

MGA
Maltase-glucoamylase

1

0

High-throughput

0.232

Low

1380951

MIPEP
Mitochondrial intermediate peptidase

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025