HitPredict

Interactor 1: MYPC2 (Q14324)
Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform)
Gene: MYBPC2

Interactor 2: COCA1 (Q99715)
Collagen alpha-1(XII) chain
Gene: COL12A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	23414517
Identification Methods	two hybrid, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	fn3~fn3, I-set~fn3
Common GO terms	GO:0007155 - cell adhesion
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1141 Hs			1 3063
+	Hs
		1053315 MYPC2_HUMAN (1-1141): 0: 688: 100.00		TITIN_HUMAN (1642-1932): 1.25e-09: 67: 10.51
+	Dm
		116147 M9PHS6_DROME (326-1140): 1.04e-59: 227: 14.09		M9PHS6_DROME (31-920): 3.41e-55: 216: 12.12
+	Dm
		1000577 Q0E8G9_DROME (438-1140): 1.02e-49: 195: 10.45		Q0E8G9_DROME (31-920): 1.43e-54: 214: 12.15
+	Mm
		1112510 SDK1_MOUSE (481-843): 2.01e-14: 80.6: 15.01		SDK1_MOUSE (6-993): 3.47e-73: 276: 14.47
+	Mm
		93890 E9QPR7_MOUSE (1-838): 2.08e-46: 185: 11.91		E9QPR7_MOUSE (3-633): 2.36e-36: 154: 10.72
+	Mm
		93891 E9QPR7_MOUSE (1-838): 2.08e-46: 185: 11.91		SDK2_MOUSE (1661-2418): 1.13e-33: 145: 8.48
+	Mm
		93892 DSCAM_MOUSE (460-1140): 2.68e-43: 175: 13.41		E9QPR7_MOUSE (3-633): 2.36e-36: 154: 10.72
+	Mm
		1167062 DSCAM_MOUSE (460-1140): 2.68e-43: 175: 13.41		SDK2_MOUSE (1661-2418): 1.13e-33: 145: 8.48
+	Mm
		1167061 SDK2_MOUSE (201-1031): 2.34e-28: 126: 12.06		SDK2_MOUSE (1661-2418): 1.13e-33: 145: 8.48
+	Hs
		616927 NRCAM_HUMAN (529-1140): 3.95e-43: 173: 13.55		PTPRB_HUMAN (9-490): 4.05e-17: 91.3: 10.97
+	Dm
		1001237 DSCA1_DROME (846-1140): 6.77e-18: 92.2: 12.50		DSCA1_DROME (8-606): 6.44e-35: 150: 11.25
+	Hs
		489957 PTPRS_HUMAN (503-867): 1.21e-14: 81.5: 12.01		PTPRF_HUMAN (1-564): 1.25e-37: 159: 10.71
+	Hs
		616914 CNTN1_HUMAN (3-727): 3.48e-34: 144: 9.88		PTPRB_HUMAN (9-490): 4.05e-17: 91.3: 10.97
+	Hs
		1060200 MYPC3_HUMAN (1-639): 2.74e-35: 148: 12.23		TITIN_HUMAN (1642-1932): 1.25e-09: 67: 10.51
+	Hs
		1031977 PTPRS_HUMAN (503-867): 1.21e-14: 81.5: 12.01		PTPRS_HUMAN (333-1003): 1.68e-29: 132: 16.18
+	Hs
		616916 PTPRS_HUMAN (503-867): 1.21e-14: 81.5: 12.01		PTPRB_HUMAN (9-490): 4.05e-17: 91.3: 10.97
+	Hs
		870000 MYOM2_HUMAN (77-540): 1.74e-20: 100: 15.08		TITIN_HUMAN (1642-1932): 1.25e-09: 67: 10.51
+	Hs
		1264775 NEO1_HUMAN (10-699): 1.72e-17: 90.6: 9.20		TITIN_HUMAN (1642-1932): 1.25e-09: 67: 10.51
+	Hs
		616971 PTPRS_HUMAN (503-867): 1.21e-14: 81.5: 12.01		PTPRD_HUMAN (1-498): 3.47e-12: 75.1: 11.22