HitPredict

Interactor 1: GNA13 (Q14344)
Guanine nucleotide-binding protein subunit alpha-13 (G alpha-13) (G-protein subunit alpha-13)
Gene: GNA13

Interactor 2: GBG12 (Q9UBI6)
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
Gene: GNG12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005834 - heterotrimeric G-protein complex GO:0005886 - plasma membrane GO:0007165 - signal transduction GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 377 Hs			1 72
+	Hs
		929153 GNA13_HUMAN (1-377): 1.27e-174: 492: 100.00		GBG3_HUMAN (3-72): 1.94e-26: 93.2: 57.75
+	Hs
		887107 GNA13_HUMAN (1-377): 1.27e-174: 492: 100.00		GBG2_HUMAN (5-72): 3.25e-26: 92.8: 62.32
+	Hs
		837678 GNA13_HUMAN (1-377): 1.27e-174: 492: 100.00		GBG4_HUMAN (6-72): 2e-24: 88.2: 57.35
+	Hs
		1053453 GNA13_HUMAN (1-377): 1.27e-174: 492: 100.00		GBG8_HUMAN (5-72): 2.87e-24: 87.8: 49.28
+	Hs
		837691 GNA13_HUMAN (1-377): 1.27e-174: 492: 100.00		GBG10_HUMAN (6-72): 4.05e-24: 87.4: 44.78
+	Hs
		229239 GNAI1_HUMAN (16-376): 2.4e-171: 483: 39.06		GBG7_HUMAN (6-72): 3.3e-27: 95.1: 77.61
+	Hs
		926667 GNAI1_HUMAN (16-376): 2.4e-171: 483: 39.06		GBG3_HUMAN (3-72): 1.94e-26: 93.2: 57.75
+	Hs
		887099 GNAI1_HUMAN (16-376): 2.4e-171: 483: 39.06		GBG2_HUMAN (5-72): 3.25e-26: 92.8: 62.32
+	Hs
		929164 GNA13_HUMAN (1-377): 1.27e-174: 492: 100.00		GBG5_HUMAN (6-72): 9.85e-23: 83.6: 46.27
+	Hs
		229233 GNAI2_HUMAN (16-376): 5.84e-169: 477: 39.61		GBG7_HUMAN (6-72): 3.3e-27: 95.1: 77.61
+	Hs
		837675 GNAI1_HUMAN (16-376): 2.4e-171: 483: 39.06		GBG4_HUMAN (6-72): 2e-24: 88.2: 57.35
+	Hs
		926724 GNAI1_HUMAN (16-376): 2.4e-171: 483: 39.06		GBG8_HUMAN (5-72): 2.87e-24: 87.8: 49.28
+	Hs
		837689 GNAI1_HUMAN (16-376): 2.4e-171: 483: 39.06		GBG10_HUMAN (6-72): 4.05e-24: 87.4: 44.78
+	Hs
		391377 GNAI2_HUMAN (16-376): 5.84e-169: 477: 39.61		GBG3_HUMAN (3-72): 1.94e-26: 93.2: 57.75
+	Hs
		391364 GNAI2_HUMAN (16-376): 5.84e-169: 477: 39.61		GBG2_HUMAN (5-72): 3.25e-26: 92.8: 62.32
+	Hs
		926668 GNAI1_HUMAN (16-376): 2.4e-171: 483: 39.06		GBG5_HUMAN (6-72): 9.85e-23: 83.6: 46.27
+	Hs
		929138 GNA13_HUMAN (1-377): 1.27e-174: 492: 100.00		GBG1_HUMAN (13-71): 8.37e-19: 73.9: 41.67
+	Hs
		391359 GNAI2_HUMAN (16-376): 5.84e-169: 477: 39.61		GBG4_HUMAN (6-72): 2e-24: 88.2: 57.35
+	Hs
		391360 GNAI2_HUMAN (16-376): 5.84e-169: 477: 39.61		GBG10_HUMAN (6-72): 4.05e-24: 87.4: 44.78
+	Hs
		391378 GNAI2_HUMAN (16-376): 5.84e-169: 477: 39.61		GBG5_HUMAN (6-72): 9.85e-23: 83.6: 46.27