Protein: AQP1
Aquaporin-1 (AQP-1) (Aquaporin-CHIP) (Urine water channel) (Water channel protein for red blood cells and kidney proximal tubule)

Gene: AQP1
Organism: Homo sapiens
Interactions: 145
UniProt ID: P29972

Gene Ontology (top 5):
GO:0003091 - renal water homeostasis
GO:0003094 - glomerular filtration
GO:0003097 - renal water transport
GO:0005223 - intracellularly cGMP-activated cation channel activity
GO:0005267 - potassium channel activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

670313

AQP1
Aquaporin-1

4

19

Small-scale

0.904

High

670331

AQP6
Aquaporin-6

2

19

High-throughput

0.783

High

670384

MDFI
MyoD family inhibitor

6

1

High-throughput

0.738

High

670334

TRIP6
Thyroid receptor-interacting protein 6

4

1

High-throughput

0.705

High

670315

TRI23
E3 ubiquitin-protein ligase TRIM23

3

5

High-throughput

0.675

High

670413

RGS17
Regulator of G-protein signaling 17

3

1

High-throughput

0.675

High

670416

IKZF3
Zinc finger protein Aiolos

3

3

High-throughput

0.675

High

670322

REL
Proto-oncogene c-Rel

3

3

High-throughput

0.650

High

670343

MTUS2
Microtubule-associated tumor suppressor candidate 2

3

0

High-throughput

0.646

High

216676

CREB3
Cyclic AMP-responsive element-binding protein 3

2

4

High-throughput

0.640

High

670357

NT2NA
Notch homolog 2 N-terminal-like protein A

2

2

High-throughput

0.633

High

670391

KRA42
Keratin-associated protein 4-2

3

10

High-throughput

0.616

High

131303

CLD5
Claudin-5

2

4

High-throughput

0.606

High

177825

TMPS2
Transmembrane protease serine 2

2

1

High-throughput

0.606

High

280857

KRT37
Keratin, type I cuticular Ha7

2

5

High-throughput

0.606

High

301636

TRI37
E3 ubiquitin-protein ligase TRIM37

2

1

High-throughput

0.606

High

310427

KCNK5
Potassium channel subfamily K member 5

2

1

High-throughput

0.606

High

554271

MUC1
Mucin-1

2

2

High-throughput

0.606

High

670316

COMP
Cartilage oligomeric matrix protein

2

1

High-throughput

0.606

High

670336

S15A2
Solute carrier family 15 member 2

2

5

High-throughput

0.606

High

670339

ZN792
Zinc finger protein 792

2

2

High-throughput

0.606

High

670344

F209A
Protein FAM209A

2

2

High-throughput

0.606

High

670346

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

2

1

High-throughput

0.606

High

670350

TENS2
Tensin-2

2

3

High-throughput

0.606

High

670358

SPRE2
Sprouty-related, EVH1 domain-containing protein 2

2

3

High-throughput

0.606

High

670359

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

2

3

High-throughput

0.606

High

670372

TRI41
E3 ubiquitin-protein ligase TRIM41

2

2

High-throughput

0.606

High

670377

LRC59
Leucine-rich repeat-containing protein 59

2

6

High-throughput

0.606

High

670395

TRIM7
E3 ubiquitin-protein ligase TRIM7

2

1

High-throughput

0.606

High

670397

PRD14
PR domain zinc finger protein 14

2

2

High-throughput

0.606

High

670402

S39A2
Zinc transporter ZIP2

2

3

High-throughput

0.606

High

670405

PRDM6
Putative histone-lysine N-methyltransferase PRDM6

2

2

High-throughput

0.606

High

670396

CEP44
Centrosomal protein of 44 kDa

2

0

High-throughput

0.601

High

66995

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.580

High

69228

MI4GD
MIF4G domain-containing protein

2

0

High-throughput

0.580

High

123365

GET1
Guided entry of tail-anchored proteins factor 1

2

0

High-throughput

0.580

High

175422

SIVA
Apoptosis regulatory protein Siva

2

0

High-throughput

0.580

High

238951

LPXN
Leupaxin

2

0

High-throughput

0.580

High

243175

G37L1
G-protein coupled receptor 37-like 1

2

0

High-throughput

0.580

High

267481

KHDR3
KH domain-containing, RNA-binding, signal transduction-associated protein 3

2

0

High-throughput

0.580

High

310132

CCDB1
Cyclin-D1-binding protein 1

2

0

High-throughput

0.580

High

320662

LDOC1
Protein LDOC1

2

0

High-throughput

0.580

High

436677

GLI1
Zinc finger protein GLI1

2

0

High-throughput

0.580

High

515994

CD79A
B-cell antigen receptor complex-associated protein alpha chain

2

0

High-throughput

0.580

High

563283

ZNF16
Zinc finger protein 16

2

0

High-throughput

0.580

High

670314

EVI2B
Protein EVI2B

2

0

High-throughput

0.580

High

670321

CDR2
Cerebellar degeneration-related protein 2

2

0

High-throughput

0.580

High

670345

SPDYA
Speedy protein A

2

0

High-throughput

0.580

High

670354

GASP3
G protein-coupled receptor associated sorting protein 3

2

0

High-throughput

0.580

High

670360

CPLX4
Complexin-4

2

0

High-throughput

0.580

High

670365

IFT20
Intraflagellar transport protein 20 homolog

2

0

High-throughput

0.580

High

670370

ZN398
Zinc finger protein 398

2

0

High-throughput

0.580

High

670381

BMF
Bcl-2-modifying factor

2

0

High-throughput

0.580

High

670386

BEGIN
Brain-enriched guanylate kinase-associated protein

2

0

High-throughput

0.580

High

670387

B2L13
Bcl-2-like protein 13

2

0

High-throughput

0.580

High

670398

GO45
Golgin-45

2

0

High-throughput

0.580

High

670400

RN122
RING finger protein 122

2

0

High-throughput

0.580

High

670401

IL21R
Interleukin-21 receptor

2

0

High-throughput

0.580

High

670407

PLS2
Phospholipid scramblase 2

2

0

High-throughput

0.580

High

670408

TM38B
Trimeric intracellular cation channel type B

2

0

High-throughput

0.580

High

670410

RBAK
RB-associated KRAB zinc finger protein

2

0

High-throughput

0.580

High

670411

ZIM2
Zinc finger imprinted 2

2

0

High-throughput

0.580

High

50896

FSD2
Fibronectin type III and SPRY domain-containing protein 2

1

4

High-throughput

0.573

High

208096

SPY2
Protein sprouty homolog 2

1

3

High-throughput

0.573

High

283165

RGS20
Regulator of G-protein signaling 20

1

1

High-throughput

0.573

High

670325

ACK1
Activated CDC42 kinase 1

1

1

High-throughput

0.573

High

670327

TRAF2
TNF receptor-associated factor 2

1

3

High-throughput

0.573

High

670329

TRAF1
TNF receptor-associated factor 1

1

1

High-throughput

0.573

High

670332

KT33B
Keratin, type I cuticular Ha3-II

1

5

High-throughput

0.573

High

670333

K1H1
Keratin, type I cuticular Ha1

1

5

High-throughput

0.573

High

670337

CCD57
Coiled-coil domain-containing protein 57

1

2

High-throughput

0.573

High

670404

CRAC1
Cartilage acidic protein 1

1

3

High-throughput

0.573

High

670412

RIM3A
RIMS-binding protein 3A

1

2

High-throughput

0.573

High

670414

TRIM1
Probable E3 ubiquitin-protein ligase MID2

1

5

High-throughput

0.573

High

670415

IKZF2
Zinc finger protein Helios

1

3

High-throughput

0.573

High

157532

MGST3
Glutathione S-transferase 3, mitochondrial

2

3

High-throughput

0.553

High

166066

ZBT39
Zinc finger and BTB domain-containing protein 39

2

1

High-throughput

0.553

High

208412

SPY3
Protein sprouty homolog 3

2

3

High-throughput

0.553

High

312705

CXB5
Gap junction beta-5 protein

2

4

High-throughput

0.553

High

623564

IBP6
Insulin-like growth factor-binding protein 6

2

2

High-throughput

0.553

High

670320

KR108
Keratin-associated protein 10-8

2

9

High-throughput

0.553

High

670323

KRA11
Keratin-associated protein 1-1

2

9

High-throughput

0.553

High

670326

GOGA2
Golgin subfamily A member 2

2

3

High-throughput

0.553

High

670353

MRM1
rRNA methyltransferase 1, mitochondrial

2

2

High-throughput

0.553

High

670364

TRI42
Tripartite motif-containing protein 42

2

4

High-throughput

0.553

High

670371

GPX8
Probable glutathione peroxidase 8

2

2

High-throughput

0.553

High

670373

SSMM1
Serine-rich single-pass membrane protein 1

2

1

High-throughput

0.553

High

670388

KRA98
Keratin-associated protein 9-8

2

10

High-throughput

0.553

High

670390

KRA44
Keratin-associated protein 4-4

2

10

High-throughput

0.553

High

670393

KRA15
Keratin-associated protein 1-5

2

10

High-throughput

0.553

High

670406

SAR1A
Small COPII coat GTPase SAR1A

2

5

High-throughput

0.553

High

551075

ITF2
Transcription factor 4

1

0

High-throughput

0.549

High

670363

SIAH1
E3 ubiquitin-protein ligase SIAH1

1

0

High-throughput

0.549

High

670383

CSRN1
Cysteine/serine-rich nuclear protein 1

1

0

High-throughput

0.549

High

327956

FBLN4
EGF-containing fibulin-like extracellular matrix protein 2

1

1

High-throughput

0.541

High

670367

KCD17
BTB/POZ domain-containing protein KCTD17

1

1

High-throughput

0.541

High

670319

KR107
Keratin-associated protein 10-7

1

9

High-throughput

0.523

High

670351

K1C40
Keratin, type I cytoskeletal 40

1

5

High-throughput

0.523

High

670356

KCTD9
BTB/POZ domain-containing protein KCTD9

1

1

High-throughput

0.523

High

670380

CC136
Coiled-coil domain-containing protein 136

1

2

High-throughput

0.523

High

670389

KRA92
Keratin-associated protein 9-2

1

10

High-throughput

0.523

High

670335

CC85B
Coiled-coil domain-containing protein 85B

1

0

High-throughput

0.518

High

670376

RN166
E3 ubiquitin-protein ligase RNF166

1

1

High-throughput

0.515

High

670417

VPP2
V-type proton ATPase 116 kDa subunit a 2

1

4

High-throughput

0.515

High

57668

A2BDD9
AMOT protein

1

3

High-throughput

0.515

High

670352

Q6FG41
Protein c-Fos

1

5

High-throughput

0.515

High

670385

KR412
Keratin-associated protein 4-12

1

10

High-throughput

0.494

High

483

NBPFJ
Neuroblastoma breakpoint family member 19

1

1

High-throughput

0.481

High

345345

FOS
Protein c-Fos

1

5

High-throughput

0.481

High

359685

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

1

High-throughput

0.481

High

670341

AMOT
Angiomotin

1

2

High-throughput

0.481

High

670348

NBPF6
Neuroblastoma breakpoint family member 6

1

1

High-throughput

0.481

High

670374

TSC1
Hamartin

1

2

High-throughput

0.481

High

502904

MYH3
Myosin-3

1

1

Small-scale

0.479

High

484571

NT2NC
Notch homolog 2 N-terminal-like protein C

1

2

High-throughput

0.470

High

670361

Q86WV8
TSC complex subunit 1

1

1

High-throughput

0.470

High

670324

PPARA
Peroxisome proliferator-activated receptor alpha

1

0

High-throughput

0.460

High

670362

NUTM1
NUT family member 1

1

0

High-throughput

0.460

High

670330

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

2

High-throughput

0.457

High

670394

TRI54
Tripartite motif-containing protein 54

1

3

High-throughput

0.457

High

670318

KR103
Keratin-associated protein 10-3

1

9

High-throughput

0.439

High

517076

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.438

High

670375

AP2C
Transcription factor AP-2 gamma

1

0

High-throughput

0.438

High

47152

A0A6Q8KRG2
Golgin subfamily A member 2

1

3

High-throughput

0.417

High

670355

ATL4
ADAMTS-like protein 4

2

0

High-throughput

0.323

High

180684

PA2GX
Group 10 secretory phospholipase A2

2

0

High-throughput

0.316

High

526741

MYF5
Myogenic factor 5

2

0

High-throughput

0.316

High

670317

KR124
Keratin-associated protein 12-4

2

0

High-throughput

0.316

High

670328

MKRN3
Probable E3 ubiquitin-protein ligase makorin-3

2

0

High-throughput

0.316

High

670338

F161A
Protein FAM161A

2

0

High-throughput

0.316

High

670340

KRA62
Keratin-associated protein 6-2

2

0

High-throughput

0.316

High

670342

KLH26
Kelch-like protein 26

2

0

High-throughput

0.316

High

670347

LCE1A
Late cornified envelope protein 1A

2

0

High-throughput

0.316

High

670349

SPRY7
SPRY domain-containing protein 7

2

0

High-throughput

0.316

High

670369

FNDC9
Fibronectin type III domain-containing protein 9

2

0

High-throughput

0.316

High

670378

TM45B
Transmembrane protein 45B

2

0

High-throughput

0.316

High

670379

TMM80
Transmembrane protein 80

2

0

High-throughput

0.316

High

670382

TM237
Transmembrane protein 237

2

0

High-throughput

0.316

High

670392

KRA32
Keratin-associated protein 3-2

2

0

High-throughput

0.316

High

670399

LIME1
Lck-interacting transmembrane adapter 1

2

0

High-throughput

0.316

High

670403

ESM1
Endothelial cell-specific molecule 1

2

0

High-throughput

0.316

High

670409

PGPI
Pyroglutamyl-peptidase 1

2

0

High-throughput

0.316

High

670366

IHO1
Interactor of HORMAD1 protein 1

1

0

High-throughput

0.299

High

670368

K1958
Uncharacterized protein KIAA1958

1

0

High-throughput

0.299

High


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Last updated: 15 Jul 2024