Interactor 1: BECN1 (Q14457)
Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197) [Cleaved into: Beclin-1-C 35 kDa; Beclin-1-C 37 kDa]
Gene: BECN1

Interactor 2: BAK (Q16611)
Bcl-2 homologous antagonist/killer (Apoptosis regulator BAK) (Bcl-2-like protein 7) (Bcl2-L-7)
Gene: BAK1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 17446862
Identification Methods fluorescence polarization spectroscopy
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains BH3~Bcl-2
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005829 - cytosol
GO:0006915 - apoptotic process
GO:0008285 - negative regulation of cell population proliferation
GO:0009410 - response to xenobiotic stimulus
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 450
Hs

1 211
+ Hs
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024