HitPredict

Interactor 1: CASL (Q14511)
Enhancer of filamentation 1 (hEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (Cas scaffolding protein family member 2) (CASS2) (Neural precursor cell expressed developmentally down-regulated protein 9) (NEDD-9) (Renal carcinoma antigen NY-REN-12) (p105) [Cleaved into: Enhancer of filamentation 1 p55]
Gene: NEDD9

Interactor 2: CASL (Q14511)
Enhancer of filamentation 1 (hEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (Cas scaffolding protein family member 2) (CASS2) (Neural precursor cell expressed developmentally down-regulated protein 9) (NEDD-9) (Renal carcinoma antigen NY-REN-12) (p105) [Cleaved into: Enhancer of filamentation 1 p55]
Gene: NEDD9

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.807

The method score is based on:

Property Details
Experiments 10502414, 8668148
Identification Methods affinity chromatography technology, two hybrid, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CAS_C~CAS_C, SH3_9~SH3_9
Common GO terms GO:0000922 - spindle pole
GO:0001772 - immunological synapse
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 33 others

more...
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 834
Hs

1 834
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024