Protein: NACC1
Nucleus accumbens-associated protein 1 (NAC-1) (BTB/POZ domain-containing protein 14B)

Gene: NACC1
Organism: Homo sapiens
Interactions: 92
UniProt ID: Q96RE7

Gene Ontology (top 5):
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1114067

CUL3
Cullin-3

2

20

Small-scale

0.806

High

1385293

ZBTB9
Zinc finger and BTB domain-containing protein 9

2

19

High-throughput

0.789

High

1401275

NACC1
Nucleus accumbens-associated protein 1

2

18

Small-scale

0.737

High

161305

ENC1
Ectoderm-neural cortex protein 1

1

20

Small-scale

0.713

High

229357

ZBT14
Zinc finger and BTB domain-containing protein 14

1

20

Small-scale

0.713

High

329096

KLHL2
Kelch-like protein 2

1

18

Small-scale

0.713

High

832771

BCL6
B-cell lymphoma 6 protein

1

19

Small-scale

0.713

High

1156075

ZBTB6
Zinc finger and BTB domain-containing protein 6

1

18

Small-scale

0.713

High

1250641

BCOR
BCL-6 corepressor

1

18

Small-scale

0.713

High

74363

ZBT42
Zinc finger and BTB domain-containing protein 42

1

19

High-throughput

0.691

High

1384562

NACC2
Nucleus accumbens-associated protein 2

1

19

High-throughput

0.691

High

573874

CCNB1
G2/mitotic-specific cyclin-B1

2

1

Small-scale

0.639

High

941044

HDAC4
Histone deacetylase 4

2

20

Small-scale

0.636

High

993717

UBC9
SUMO-conjugating enzyme UBC9

2

20

Small-scale

0.629

High

1115014

CUL4A
Cullin-4A

1

20

Small-scale

0.618

High

1332698

ZBT38
Zinc finger and BTB domain-containing protein 38

1

20

Small-scale

0.618

High

127389

LEG8
Galectin-8

2

2

High-throughput

0.606

High

215171

PRPF3
U4/U6 small nuclear ribonucleoprotein Prp3

2

1

High-throughput

0.606

High

506172

UBFL1
Upstream-binding factor 1-like protein 1

2

18

High-throughput

0.606

High

835736

KPCI
Protein kinase C iota type

2

10

High-throughput

0.606

High

974273

LSM3
U6 snRNA-associated Sm-like protein LSm3

2

4

High-throughput

0.606

High

983693

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

2

1

High-throughput

0.606

High

1124397

ELOA1
Elongin-A

2

9

High-throughput

0.606

High

1396109

Z512B
Zinc finger protein 512B

2

20

High-throughput

0.606

High

1401277

PRP18
Pre-mRNA-splicing factor 18

2

1

High-throughput

0.606

High

173251

XPO1
Exportin-1

2

16

Small-scale

0.584

High

242653

PRKN
E3 ubiquitin-protein ligase parkin

2

20

Small-scale

0.584

High

337512

MATN4
Matrilin-4

2

6

High-throughput

0.574

High

188345

HDAC3
Histone deacetylase 3

1

20

Small-scale

0.573

High

788752

SRP14
Signal recognition particle 14 kDa protein

1

2

High-throughput

0.536

High

937862

FOXA1
Hepatocyte nuclear factor 3-alpha

1

16

High-throughput

0.536

High

1054770

SUH
Recombining binding protein suppressor of hairless

1

3

High-throughput

0.536

High

1401278

M3K5
Mitogen-activated protein kinase kinase kinase 5

1

16

High-throughput

0.536

High

1401281

FOXP3
Forkhead box protein P3

1

20

High-throughput

0.536

High

1401287

FOXJ2
Forkhead box protein J2

1

19

High-throughput

0.536

High

1401294

FOXA2
Hepatocyte nuclear factor 3-beta

1

15

High-throughput

0.536

High

1087961

NFIA
Nuclear factor 1 A-type

1

20

High-throughput

0.515

High

1133617

NFIX
Nuclear factor 1 X-type

1

20

High-throughput

0.515

High

281240

CDC45
Cell division control protein 45 homolog

1

0

High-throughput

0.513

High

333594

NDUC2
NADH dehydrogenase [ubiquinone] 1 subunit C2

1

0

High-throughput

0.513

High

714363

PML
Protein PML

1

20

Small-scale

0.501

High

1096175

TADBP
TAR DNA-binding protein 43

1

15

Small-scale

0.501

High

1401284

SENP2
Sentrin-specific protease 2

1

7

Small-scale

0.501

High

1401288

SENP1
Sentrin-specific protease 1

1

7

Small-scale

0.501

High

1401282

GREM2
Gremlin-2

1

1

High-throughput

0.489

High

1401285

TBA8
Tubulin alpha-8 chain

1

8

High-throughput

0.481

High

138754

IMA4
Importin subunit alpha-4

1

16

Small-scale

0.479

High

142610

IMA3
Importin subunit alpha-3

1

16

Small-scale

0.479

High

143205

NFIB
Nuclear factor 1 B-type

1

20

High-throughput

0.479

High

260331

BRD4
Bromodomain-containing protein 4

1

15

High-throughput

0.479

High

372903

MYC
Myc proto-oncogene protein

1

17

High-throughput

0.479

High

396756

ESR1
Estrogen receptor

1

20

High-throughput

0.479

High

404350

GCR
Glucocorticoid receptor

1

20

High-throughput

0.479

High

474226

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.479

High

696268

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

6

High-throughput

0.479

High

768945

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.479

High

776234

SOX6
Transcription factor SOX-6

1

20

High-throughput

0.479

High

800061

COIL
Coilin

1

5

High-throughput

0.479

High

881588

CDK8
Cyclin-dependent kinase 8

1

9

High-throughput

0.479

High

887144

CEBPA
CCAAT/enhancer-binding protein alpha

1

19

High-throughput

0.479

High

906585

PSMD7
26S proteasome non-ATPase regulatory subunit 7

1

14

Small-scale

0.479

High

1017138

H33
Histone H3.3

1

10

High-throughput

0.479

High

1092917

STRN3
Striatin-3

1

14

High-throughput

0.479

High

1097506

CBX3
Chromobox protein homolog 3

1

20

High-throughput

0.479

High

1137469

SUZ12
Polycomb protein SUZ12

1

4

High-throughput

0.479

High

1155683

EZH2
Histone-lysine N-methyltransferase EZH2

1

20

High-throughput

0.479

High

1220752

RN123
E3 ubiquitin-protein ligase RNF123

1

9

High-throughput

0.479

High

1255153

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.479

High

1276671

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

7

High-throughput

0.479

High

1289554

NAA40
N-alpha-acetyltransferase 40

1

2

High-throughput

0.479

High

1351132

SP7
Transcription factor Sp7

1

20

High-throughput

0.479

High

1363950

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

1

High-throughput

0.479

High

1364213

TOPB1
DNA topoisomerase 2-binding protein 1

1

9

High-throughput

0.479

High

1364530

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.479

High

1401279

DDA1
DET1- and DDB1-associated protein 1

1

4

High-throughput

0.479

High

1401286

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

2

High-throughput

0.479

High

1401289

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

1401290

TBK1
Serine/threonine-protein kinase TBK1

1

11

Small-scale

0.479

High

1401291

DS13B
Dual specificity protein phosphatase 13B

1

3

High-throughput

0.479

High

1401292

NUP50
Nuclear pore complex protein Nup50

1

2

High-throughput

0.479

High

1401293

BRPF3
Bromodomain and PHD finger-containing protein 3

1

14

High-throughput

0.479

High

1064010

ECHP
Peroxisomal bifunctional enzyme

1

8

High-throughput

0.470

High

459728

PROF1
Profilin-1

1

0

Small-scale

0.458

High

1401276

CDC5L
Cell division cycle 5-like protein

1

6

High-throughput

0.445

High

1401280

IFIH1
Interferon-induced helicase C domain-containing protein 1

1

6

Small-scale

0.445

High

1278079

MAVS
Mitochondrial antiviral-signaling protein

1

9

Small-scale

0.437

High

1111210

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.426

High

1331662

RM43
Large ribosomal subunit protein mL43

3

0

High-throughput

0.347

High

1359095

ITLN1
Intelectin-1

3

0

High-throughput

0.347

High

1401283

CH033
UPF0488 protein C8orf33

2

0

High-throughput

0.316

High

1181025

DB136
Defensin beta 136

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025