HitPredict

Interactor 1: APRIO (F7VJQ1)
Alternative prion protein (AltPrP)
Gene: PRNP

Interactor 2: MP2K4 (P45985)
Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase 4) (MAPKK 4) (EC 2.7.12.2) (JNK-activating kinase 1) (MAPK/ERK kinase 4) (MEK 4) (SAPK/ERK kinase 1) (SEK1) (Stress-activated protein kinase kinase 1) (SAPK kinase 1) (SAPKK-1) (SAPKK1) (c-Jun N-terminal kinase kinase 1) (JNKK)
Gene: MAP2K4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	33618749
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 73 Hs			1 399
+	Hs
		105779 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		KPCE_HUMAN (24-398): 9.38e-122: 371: 18.30
+	Hs
		105284 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		KAPCA_HUMAN (66-399): 7.35e-122: 358: 18.82
+	Hs
		105857 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		PAK1_HUMAN (19-368): 1.28e-99: 308: 28.06
+	Hs
		104814 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		STK25_HUMAN (85-387): 7.47e-98: 299: 32.46
+	Hs
		105784 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		MP2K1_HUMAN (100-393): 1.73e-60: 202: 36.20