Interactor 1: G5ECY6 (G5ECY6)
E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (RING-type E3 ubiquitin transferase CHIP)
Gene: chn-1

Interactor 2: UBE4 (Q09349)
Ubiquitin conjugation factor E4 ufd-2 (EC 2.3.2.27) (E4 ubiquitin-protein ligase ufd-2) (RING-type E3 ubiquitin transferase E4) (Ubiquitin fusion degradation protein 2)
Gene: ufd-2

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.826

The method score is based on:

Property Details
Experiments 17369820, 15294159
Identification Methods affinity chromatography technology, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CHIP_TPR_N~U-box, U-box~U-box
Common GO terms GO:0000209 - protein polyubiquitination
GO:0005737 - cytoplasm
GO:0008340 - determination of adult lifespan
GO:0016567 - protein ubiquitination
GO:0031625 - ubiquitin protein ligase binding
and 4 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 266
Ce

1 984
+ Mm
+ Hs
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024