HitPredict

Interactor 1: G5EEI1 (G5EEI1)
LGL-1 (Lethal giant larvae homologue 2 domain-containing protein)
Gene: lgl-1

Interactor 2: KPC3 (Q19266)
Protein kinase C-like 3 (EC 2.7.11.13) (Atypical protein kinase C-3) (aPKC3)
Gene: pkc-3

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	27720986, 20579886, 27506200
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005938 - cell cortex GO:0008104 - protein localization GO:0030864 - cortical actin cytoskeleton
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 941 Ce			1 597
+	Mm
		1111901 L2GL2_MOUSE (4-932): 0: 1010: 19.49		KPCI_MOUSE (1-597): 0: 667: 56.36
+	Hs
		784012 L2GL1_HUMAN (5-931): 0: 1009: 19.49		KPCI_HUMAN (1-597): 0: 668: 55.69
+	Hs
		784030 L2GL2_HUMAN (4-932): 0: 1009: 19.28		KPCI_HUMAN (1-597): 0: 668: 55.69
+	Mm
		1143282 L2GL1_MOUSE (5-931): 0: 1001: 19.59		KPCI_MOUSE (1-597): 0: 667: 56.36
+	Hs
		983844 L2GL1_HUMAN (5-931): 0: 1009: 19.49		KPCZ_HUMAN (2-597): 0: 628: 55.28
+	Hs
		983860 L2GL2_HUMAN (4-932): 0: 1009: 19.28		KPCZ_HUMAN (2-597): 0: 628: 55.28
+	Mm
		973812 L2GL1_MOUSE (5-931): 0: 1001: 19.59		KPCZ_MOUSE (2-597): 0: 631: 55.28
+	Dm
		54639 L2GL_DROME (4-931): 0: 855: 18.07		APKC_DROME (2-597): 0: 621: 55.11
+	Rn
		1144332 L2GL1_RAT (5-931): 0: 997: 19.49		AKT3_RAT (194-587): 3.86e-149: 440: 34.75