Interactor 1: IHH (Q14623)
Indian hedgehog protein (IHH) (EC 3.1.-.-) (HHG-2) [Cleaved into: Indian hedgehog protein N-product]
Gene: IHH

Interactor 2: CDON (Q4KMG0)
Cell adhesion molecule-related/down-regulated by oncogenes
Gene: CDON

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 20519495
Identification Methods x-ray crystallography
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains HH_signal~fn3
Common GO terms GO:0001708 - cell fate specification
GO:0005886 - plasma membrane
GO:0007224 - smoothened signaling pathway
GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 411
Hs

1 1287
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024