Interactor 1: TRIPC (Q14669)
E3 ubiquitin-protein ligase TRIP12 (EC 2.3.2.26) (E3 ubiquitin-protein ligase for Arf) (ULF) (HECT-type E3 ubiquitin transferase TRIP12) (Thyroid receptor-interacting protein 12) (TR-interacting protein 12) (TRIP-12)
Gene: TRIP12

Interactor 2: HECD1 (Q9ULT8)
E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1)
Gene: HECTD1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 35915203
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HECT~HECT
Common GO terms GO:0016607 - nuclear speck
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0061630 - ubiquitin protein ligase activity
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 1992
Hs

1 2610
+ Hs
+ Hs
+ Sc
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024