Interactor 1: SMC1A (Q14683)
Structural maintenance of chromosomes protein 1A (SMC protein 1A) (SMC-1-alpha) (SMC-1A) (Sb1.8)
Gene: SMC1A

Interactor 2: NIPBL (Q6KC79)
Nipped-B-like protein (Delangin) (SCC2 homolog)
Gene: NIPBL

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.847

The method score is based on:

Property Details
Experiments 31010829, 35271311, 20720539
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Nipped-B_C~SMC_N
Common GO terms GO:0000070 - mitotic sister chromatid segregation
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
and 4 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 1233
Hs

1 2804
+ Mm
+ Hs
+ Mm
+ Sc
+ Sc
+ Sc
+ Sp
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024