HitPredict

Interactor 1: SMC1A (Q14683)
Structural maintenance of chromosomes protein 1A (SMC protein 1A) (SMC-1-alpha) (SMC-1A) (Sb1.8)
Gene: SMC1A

Interactor 2: HDA11 (Q96DB2)
Histone deacetylase 11 (HD11) (EC 3.5.1.98)
Gene: HDAC11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	23752268
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1233 Hs			1 347
+	Hs
		1038754 SMC4_HUMAN (4-1216): 2.64e-76: 278: 19.90		HDAC1_HUMAN (13-330): 8.87e-140: 407: 22.89
+	Hs
		1288036 SMC4_HUMAN (4-1216): 2.64e-76: 278: 19.90		HDA11_HUMAN (1-347): 1.17e-140: 403: 100.00
+	Hs
		1288057 SMC3_HUMAN (3-1229): 1.52e-70: 260: 16.00		HDA11_HUMAN (1-347): 1.17e-140: 403: 100.00
+	Hs
		311598 SMC2_HUMAN (3-1214): 1.55e-77: 281: 17.57		HDAC2_HUMAN (13-330): 4.9e-128: 376: 22.89
+	Hs
		1356595 SMC3_HUMAN (3-1229): 1.52e-70: 260: 16.00		HDAC9_HUMAN (1-346): 9.62e-128: 391: 20.47
+	Hs
		1270533 SMC3_HUMAN (3-1229): 1.52e-70: 260: 16.00		HDAC2_HUMAN (13-330): 4.9e-128: 376: 22.89
+	Hs
		724813 MYH9_HUMAN (49-760): 1.43e-25: 117: 11.62		HDAC1_HUMAN (13-330): 8.87e-140: 407: 22.89
+	Hs
		528410 MYH8_HUMAN (518-1125): 3.54e-20: 99.8: 9.36		HDAC1_HUMAN (13-330): 8.87e-140: 407: 22.89
+	Hs
		1038808 MYH2_HUMAN (495-1125): 5.14e-20: 99: 9.49		HDAC1_HUMAN (13-330): 8.87e-140: 407: 22.89
+	Hs
		522547 MYH1_HUMAN (563-1127): 7e-19: 95.6: 8.66		HDAC1_HUMAN (13-330): 8.87e-140: 407: 22.89
+	Hs
		1057383 SMC1A_HUMAN (1-1233): 1.94e-128: 427: 100.00		HDAC8_HUMAN (19-310): 9.6e-14: 73.6: 25.97
+	Hs
		1038853 MYH4_HUMAN (659-1132): 9.83e-17: 88.2: 10.58		HDAC1_HUMAN (13-330): 8.87e-140: 407: 22.89
+	Hs
		724945 MYH9_HUMAN (49-760): 1.43e-25: 117: 11.62		HDAC2_HUMAN (13-330): 4.9e-128: 376: 22.89
+	Hs
		522611 MYH7_HUMAN (51-420): 1.04e-10: 68.6: 13.37		HDAC1_HUMAN (13-330): 8.87e-140: 407: 22.89
+	Hs
		725053 MYH9_HUMAN (49-760): 1.43e-25: 117: 11.62		HDAC6_HUMAN (18-346): 8.68e-95: 307: 21.31
+	Sc
		810788 SMC3_YEAST (3-1215): 1.17e-78: 285: 18.20		HOS1_YEAST (130-304): 2.01e-13: 72.8: 29.51
+	Hs
		1316068 SMC3_HUMAN (3-1229): 1.52e-70: 260: 16.00		HDAC8_HUMAN (19-310): 9.6e-14: 73.6: 25.97