HitPredict

Interactor 1: RRP1B (Q14684)
Ribosomal RNA processing protein 1 homolog B (RRP1-like protein B)
Gene: RRP1B

Interactor 2: SRPK3 (Q9UPE1)
SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) (MSSK-1) (Serine/arginine-rich protein-specific kinase 3) (SR-protein-specific kinase 3) (Serine/threonine-protein kinase 23)
Gene: SRPK3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	32707033, 23602568
Identification Methods	affinity chromatography technology, pull down, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 567
+	Hs
		880071 RRP1_HUMAN (7-472): 2.2e-106: 334: 44.78		SRPK3_HUMAN (27-567): 5.16e-140: 418: 100.00
+	Hs
		942661 RRP1B_HUMAN (1-758): 6.96e-155: 470: 100.00		SRPK2_HUMAN (297-566): 8.12e-72: 244: 57.69
+	Hs
		835758 RRP1B_HUMAN (1-758): 6.96e-155: 470: 100.00		GSK3B_HUMAN (23-336): 1.58e-67: 226: 16.87
+	Hs
		1057598 RRP1B_HUMAN (1-758): 6.96e-155: 470: 100.00		SRPK1_HUMAN (368-566): 2.74e-59: 210: 67.84
+	Hs
		1057480 RRP1B_HUMAN (1-758): 6.96e-155: 470: 100.00		MK14_HUMAN (66-259): 1.61e-45: 165: 21.78
+	Hs
		879987 RRP1_HUMAN (7-472): 2.2e-106: 334: 44.78		SRPK2_HUMAN (297-566): 8.12e-72: 244: 57.69
+	Hs
		834042 RRP1B_HUMAN (1-758): 6.96e-155: 470: 100.00		CLK3_HUMAN (396-565): 4.23e-12: 70.9: 25.97
+	Hs
		834009 RRP1_HUMAN (7-472): 2.2e-106: 334: 44.78		CLK3_HUMAN (396-565): 4.23e-12: 70.9: 25.97
+	Hs
		942726 MAP1S_HUMAN (311-755): 7.34e-20: 97.2: 16.78		SRPK2_HUMAN (297-566): 8.12e-72: 244: 57.69
+	Hs
		257676 ANR17_HUMAN (197-757): 9.17e-25: 113: 9.35		DYRK2_HUMAN (344-565): 4.02e-65: 224: 25.82
+	Hs
		625528 TITIN_HUMAN (224-747): 2.27e-09: 63.3: 9.36		CDK2_HUMAN (274-566): 4.84e-82: 260: 17.97
+	Hs
		942845 TITIN_HUMAN (224-747): 2.27e-09: 63.3: 9.36		SRPK2_HUMAN (297-566): 8.12e-72: 244: 57.69
+	Hs
		554284 MUC1_HUMAN (385-755): 2.46e-11: 69.5: 8.90		GSK3B_HUMAN (23-336): 1.58e-67: 226: 16.87
+	Hs
		1264773 TITIN_HUMAN (224-747): 2.27e-09: 63.3: 9.36		DYRK2_HUMAN (344-565): 4.02e-65: 224: 25.82
+	Hs
		1082593 KMT2C_HUMAN (211-746): 8e-10: 64.9: 9.09		MK14_HUMAN (66-259): 1.61e-45: 165: 21.78