Protein: RL18B
Large ribosomal subunit protein eL18B (60S ribosomal protein L18-B) (RP28)

Gene: RL18B, RPL18B
Organism: Saccharomyces cerevisiae S288C
Interactions: 208
UniProt ID: P0CX50

Gene Ontology (top 5):
GO:0002181 - cytoplasmic translation
GO:0003723 - RNA binding
GO:0003735 - structural constituent of ribosome
GO:0005829 - cytosol
GO:0022625 - cytosolic large ribosomal subunit

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

432456

RL7A
Large ribosomal subunit protein uL30A

4

2

High-throughput

0.873

High

383248

RL28
Large ribosomal subunit protein uL15

2

1

High-throughput

0.754

High

513940

RL4A
Large ribosomal subunit protein uL4A

2

2

High-throughput

0.754

High

514008

RL13B
Large ribosomal subunit protein eL13B

2

2

High-throughput

0.754

High

514027

RL4B
Large ribosomal subunit protein uL4B

2

2

High-throughput

0.754

High

514077

RL7B
Large ribosomal subunit protein uL30B

2

2

High-throughput

0.754

High

392085

HSP82
ATP-dependent molecular chaperone HSP82

3

1

High-throughput

0.642

High

513938

HSP71
Heat shock protein SSA1

3

1

High-throughput

0.640

High

513983

GBLP
Small ribosomal subunit protein RACK1

3

5

Small-scale

0.640

High

514083

RL13A
Large ribosomal subunit protein eL13A

1

2

High-throughput

0.618

High

154121

RL36B
Large ribosomal subunit protein eL36B

2

2

High-throughput

0.584

High

427093

RLA0
Large ribosomal subunit protein uL10

2

2

High-throughput

0.584

High

433379

RL26A
Large ribosomal subunit protein uL24A

2

2

High-throughput

0.584

High

481947

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

2

1

High-throughput

0.584

High

503734

RL27A
Large ribosomal subunit protein eL27A

2

1

High-throughput

0.584

High

511114

RL20B
Large ribosomal subunit protein eL20B

2

1

High-throughput

0.584

High

513607

RL2A
Large ribosomal subunit protein uL2A

2

1

High-throughput

0.584

High

513932

RL18B
Large ribosomal subunit protein eL18B

2

1

High-throughput

0.584

High

513943

RL3
Large ribosomal subunit protein uL3

2

1

High-throughput

0.584

High

513958

CDC48
Cell division control protein 48

2

2

Small-scale

0.584

High

513960

RL5
Large ribosomal subunit protein uL18

2

1

High-throughput

0.584

High

513961

RL16A
Large ribosomal subunit protein uL13A

2

3

High-throughput

0.584

High

514016

RL10
Large ribosomal subunit protein uL16

2

1

High-throughput

0.584

High

409870

RL25
Large ribosomal subunit protein uL23

2

0

High-throughput

0.559

High

434223

RL29
Large ribosomal subunit protein eL29

2

0

High-throughput

0.559

High

434734

RS3
Small ribosomal subunit protein uS3

2

0

High-throughput

0.559

High

513955

SIS1
Protein SIS1

2

0

High-throughput

0.559

High

514073

TMA46
Translation machinery-associated protein 46

2

0

High-throughput

0.559

High

513975

RRP1
Ribosomal RNA-processing protein 1

1

2

High-throughput

0.553

High

513980

RPF2
Ribosome biogenesis protein RPF2

2

2

High-throughput

0.549

High

514040

NOG2
Nucleolar GTP-binding protein 2

2

4

Small-scale

0.533

High

514057

ARX1
Probable metalloprotease ARX1

2

2

High-throughput

0.533

High

383454

RS17A
Small ribosomal subunit protein eS17A

1

1

High-throughput

0.479

High

427527

RLA1
Large ribosomal subunit protein P1A

1

1

High-throughput

0.479

High

432780

RL9A
Large ribosomal subunit protein uL6A

1

2

High-throughput

0.479

High

432959

RL6B
Large ribosomal subunit protein eL6B

1

1

High-throughput

0.479

High

433123

RL17A
Large ribosomal subunit protein uL22A

1

1

High-throughput

0.479

High

433951

RL33A
Large ribosomal subunit protein eL33A

1

1

High-throughput

0.479

High

434125

RL36A
Large ribosomal subunit protein eL36A

1

2

High-throughput

0.479

High

434497

RL22A
Large ribosomal subunit protein eL22A

1

1

High-throughput

0.479

High

436287

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

2

High-throughput

0.479

High

438583

SC160
Protein SCP160

1

2

High-throughput

0.479

High

452548

C1TC
C-1-tetrahydrofolate synthase, cytoplasmic

1

1

High-throughput

0.479

High

453370

PYR1
Multifunctional protein URA2

1

1

High-throughput

0.479

High

503340

RL11A
Large ribosomal subunit protein uL5A

1

2

High-throughput

0.479

High

503881

RL27B
Large ribosomal subunit protein eL27B

1

1

High-throughput

0.479

High

511356

RL43B
Large ribosomal subunit protein eL43B

1

1

High-throughput

0.479

High

511997

RS4A
Small ribosomal subunit protein eS4A

1

1

High-throughput

0.479

High

512192

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.479

High

512751

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.479

High

513439

RL1A
Large ribosomal subunit protein uL1A

1

2

High-throughput

0.479

High

513935

RL19B
Large ribosomal subunit protein eL19

1

1

High-throughput

0.479

High

513936

RL35A
Large ribosomal subunit protein uL29A

1

1

High-throughput

0.479

High

513939

RLA3
Large ribosomal subunit protein P1B

1

1

High-throughput

0.479

High

513946

RL8A
Large ribosomal subunit protein eL8A

1

2

High-throughput

0.479

High

513951

RS3A2
Small ribosomal subunit protein eS1B

1

2

High-throughput

0.479

High

513956

RS2
Small ribosomal subunit protein uS5

1

2

High-throughput

0.479

High

513959

SPB4
ATP-dependent rRNA helicase SPB4

1

5

High-throughput

0.479

High

513962

RL16B
Large ribosomal subunit protein uL13B

1

3

High-throughput

0.479

High

513965

RL8B
Large ribosomal subunit protein eL8B

1

2

High-throughput

0.479

High

513967

EF2
Elongation factor 2

1

1

High-throughput

0.479

High

513968

ZUO1
Zuotin

1

2

High-throughput

0.479

High

513971

RSSA1
Small ribosomal subunit protein uS2A

1

1

High-throughput

0.479

High

513974

RS3A1
Small ribosomal subunit protein eS1A

1

2

High-throughput

0.479

High

513979

RL14A
Large ribosomal subunit protein eL14A

1

2

High-throughput

0.479

High

513988

IF5
Eukaryotic translation initiation factor 5

1

1

High-throughput

0.479

High

513990

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

513992

RL14B
Large ribosomal subunit protein eL14B

1

2

High-throughput

0.479

High

513994

SSZ1
Ribosome-associated complex subunit SSZ1

1

1

High-throughput

0.479

High

514004

NUG1
Nuclear GTP-binding protein NUG1

1

4

High-throughput

0.479

High

514010

RL34B
Large ribosomal subunit protein eL34B

1

1

High-throughput

0.479

High

514014

NOP2
25S rRNA

1

2

Small-scale

0.479

High

514015

RL33B
Large ribosomal subunit protein eL33B

1

1

High-throughput

0.479

High

514020

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

1

High-throughput

0.479

High

514021

RL17B
Large ribosomal subunit protein uL22B

1

1

High-throughput

0.479

High

514026

RL37A
Large ribosomal subunit protein eL37A

1

1

High-throughput

0.479

High

514028

RL9B
Large ribosomal subunit protein uL6B

1

2

High-throughput

0.479

High

514029

RL37B
Large ribosomal subunit protein eL37B

1

1

High-throughput

0.479

High

514034

LSG1
Large subunit GTPase 1

1

4

High-throughput

0.479

High

514035

RL26B
Large ribosomal subunit protein uL24B

1

2

High-throughput

0.479

High

514039

BRE5
UBP3-associated protein BRE5

1

2

High-throughput

0.479

High

514041

ESF2
Pre-rRNA-processing protein ESF2

1

1

Small-scale

0.479

High

514043

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

2

High-throughput

0.479

High

514044

NOP15
Ribosome biogenesis protein 15

1

1

High-throughput

0.479

High

514048

RL22B
Large ribosomal subunit protein eL22B

1

1

High-throughput

0.479

High

514049

RL34A
Large ribosomal subunit protein eL34A

1

1

High-throughput

0.479

High

514050

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

1

High-throughput

0.479

High

514052

RL6A
Large ribosomal subunit protein eL6A

1

1

High-throughput

0.479

High

514053

RL21A
Large ribosomal subunit protein eL21A

1

2

High-throughput

0.479

High

514054

NOG1
Nucleolar GTP-binding protein 1

1

4

High-throughput

0.479

High

514056

HAS1
ATP-dependent RNA helicase HAS1

1

6

High-throughput

0.479

High

514059

DHR1
Probable ATP-dependent RNA helicase DHR1

1

1

High-throughput

0.479

High

514062

RRP5
rRNA biogenesis protein RRP5

1

1

High-throughput

0.479

High

514064

IMB1
Importin subunit beta-1

1

2

Small-scale

0.479

High

514066

NOC4
Nucleolar complex protein 4

1

3

High-throughput

0.479

High

514079

DBP10
ATP-dependent RNA helicase DBP10

1

8

High-throughput

0.479

High

514080

AIR2
Protein AIR2

1

4

High-throughput

0.479

High

514082

RL21B
Large ribosomal subunit protein eL21B

1

2

High-throughput

0.479

High

514084

RL11B
Large ribosomal subunit protein uL5B

1

2

High-throughput

0.479

High

149522

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

382798

RMAR
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.458

High

383064

RLA4
Large ribosomal subunit protein P2B

1

0

High-throughput

0.458

High

409673

RL24A
Large ribosomal subunit protein eL24A

1

0

High-throughput

0.458

High

414977

RL39
Large ribosomal subunit protein eL39

1

0

High-throughput

0.458

High

416183

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

434303

RL15A
Large ribosomal subunit protein eL15A

1

0

High-throughput

0.458

High

435705

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

438366

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

0

High-throughput

0.458

High

441640

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

454805

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

502779

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.458

High

503976

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.458

High

511530

RL44B
Large ribosomal subunit protein eL42B

1

0

High-throughput

0.458

High

513933

RL12B
Large ribosomal subunit protein uL11B

1

0

High-throughput

0.458

High

513934

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

513957

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.458

High

513963

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

513966

HS104
Heat shock protein 104

1

0

High-throughput

0.458

High

513969

ECM32
Putative ATP-dependent RNA helicase ECM32

1

0

High-throughput

0.458

High

513972

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

513977

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

513984

RL32
Large ribosomal subunit protein eL32

1

0

High-throughput

0.458

High

513985

GID4
GID complex substrate-recognition subunit 4

1

0

High-throughput

0.458

High

513997

RIX1
Pre-rRNA-processing protein RIX1

1

0

Small-scale

0.458

High

514001

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

514002

IF2P
Eukaryotic translation initiation factor 5B

1

0

High-throughput

0.458

High

514024

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

514030

UFD1
Ubiquitin fusion degradation protein 1

1

0

Small-scale

0.458

High

514031

DXO
Decapping nuclease RAI1

1

0

Small-scale

0.458

High

514033

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

0

High-throughput

0.458

High

514036

PESC
Pescadillo homolog

1

0

High-throughput

0.458

High

514051

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

514060

VMS1
tRNA endonuclease VMS1

1

0

High-throughput

0.458

High

514061

LTN1
E3 ubiquitin-protein ligase listerin

1

0

Small-scale

0.458

High

514071

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.458

High

514075

YRA1
RNA annealing protein YRA1

1

0

High-throughput

0.458

High

514081

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.458

High

514085

TFB5
General transcription and DNA repair factor IIH subunit TFB5

1

0

Small-scale

0.458

High

514007

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

513999

CIN4
GTP-binding protein CIN4

1

1

Small-scale

0.439

High

364265

CDK1
Cyclin-dependent kinase 1

1

1

High-throughput

0.437

High

444400

DED1
ATP-dependent RNA helicase DED1

1

2

High-throughput

0.437

High

486383

TBA3
Tubulin alpha-3 chain

1

1

High-throughput

0.437

High

488903

SWI6
Regulatory protein SWI6

1

1

High-throughput

0.437

High

513954

NAP1
Nucleosome assembly protein

1

3

Small-scale

0.437

High

513973

MRT4
Ribosome assembly factor MRT4

1

2

Small-scale

0.437

High

513976

SKI2
Antiviral helicase SKI2

1

2

High-throughput

0.437

High

513982

NOP4
Nucleolar protein 4

1

1

High-throughput

0.437

High

513989

SRP72
Signal recognition particle subunit SRP72

1

1

High-throughput

0.437

High

513991

ECM29
Proteasome component ECM29

1

2

High-throughput

0.437

High

513998

SEC31
Protein transport protein SEC31

1

4

High-throughput

0.437

High

514000

DHH1
ATP-dependent RNA helicase DHH1

1

5

High-throughput

0.437

High

514003

NOC2
Nucleolar complex protein 2

1

1

Small-scale

0.437

High

514005

IMB4
Importin subunit beta-4

1

2

High-throughput

0.437

High

514006

NSA2
Ribosome biogenesis protein NSA2

1

1

High-throughput

0.437

High

514017

MPG1
Mannose-1-phosphate guanyltransferase

1

1

High-throughput

0.437

High

514018

ELP2
Elongator complex protein 2

1

4

High-throughput

0.437

High

514022

MTR4
ATP-dependent RNA helicase DOB1

1

2

High-throughput

0.437

High

514037

YG3A
Uncharacterized protein YGR130C

1

2

Small-scale

0.437

High

514042

GIS2
Zinc finger protein GIS2

1

4

High-throughput

0.437

High

514047

ORC1
Origin recognition complex subunit 1

1

2

High-throughput

0.437

High

514055

TOM1
E3 ubiquitin-protein ligase TOM1

1

2

High-throughput

0.437

High

514069

REXO4
RNA exonuclease 4

1

2

High-throughput

0.437

High

514072

AP3D
AP-3 complex subunit delta

1

1

High-throughput

0.437

High

514076

MAK21
Ribosome biogenesis protein MAK21

1

3

High-throughput

0.437

High

514078

SMT3
Ubiquitin-like protein SMT3

1

2

High-throughput

0.437

High

513995

RPF1
Ribosome production factor 1

1

1

High-throughput

0.407

High

514011

ULP2
Ubiquitin-like-specific protease 2

2

0

Small-scale

0.306

High

513941

CAF20
Cap-associated protein CAF20

2

0

High-throughput

0.305

High

514013

DSN1
Kinetochore-associated protein DSN1

2

0

High-throughput

0.305

High

513937

SSBP1
Single-stranded nucleic acid-binding protein

1

0

High-throughput

0.261

Low

514032

SNT2
E3 ubiquitin-protein ligase SNT2

1

0

Small-scale

0.261

Low

513947

MYO2
Myosin-2

1

0

Small-scale

0.251

Low

368115

THDH
Threonine dehydratase, mitochondrial

1

0

High-throughput

0.249

Low

386534

TBB
Tubulin beta chain

1

0

High-throughput

0.249

Low

416069

SYTC
Threonine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.249

Low

513942

ACOX
Acyl-coenzyme A oxidase

1

0

High-throughput

0.249

Low

513944

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.249

Low

513945

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.249

Low

513948

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

0

High-throughput

0.249

Low

513949

DAL82
Protein DAL82

1

0

High-throughput

0.249

Low

513950

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

0

High-throughput

0.249

Low

513952

PSA2
Proteasome subunit alpha type-2

1

0

High-throughput

0.249

Low

513953

DBP2
ATP-dependent RNA helicase DBP2

1

0

High-throughput

0.249

Low

513964

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

513970

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

0

High-throughput

0.249

Low

513978

EAP1
Protein EAP1

1

0

High-throughput

0.249

Low

513981

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

0

High-throughput

0.249

Low

513986

ENP1
Essential nuclear protein 1

1

0

High-throughput

0.249

Low

513987

YB8A
Putative uncharacterized protein YBR285W

1

0

Small-scale

0.249

Low

513993

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.249

Low

513996

YHS7
Uncharacterized protein YHR127W

1

0

High-throughput

0.249

Low

514009

TM108
Protein TMA108

1

0

High-throughput

0.249

Low

514012

SNL1
HSP70 co-chaperone SNL1

1

0

Small-scale

0.249

Low

514019

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.249

Low

514023

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.249

Low

514025

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

514038

H1
Histone H1

1

0

High-throughput

0.249

Low

514045

NST1
Stress response protein NST1

1

0

High-throughput

0.249

Low

514046

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.249

Low

514058

RRP17
Ribosomal RNA-processing protein 17

1

0

High-throughput

0.249

Low

514063

RQC1
Ribosome quality control complex subunit 1

1

0

Small-scale

0.249

Low

514065

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

514067

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

514068

BUD20
Bud site selection protein 20

1

0

High-throughput

0.249

Low

514070

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

514074

NOP53
Ribosome biogenesis protein NOP53

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025