HitPredict

Interactor 1: NCOA6 (Q14686)
Nuclear receptor coactivator 6 (Activating signal cointegrator 2) (ASC-2) (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Nuclear receptor-activating protein, 250 kDa) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Thyroid hormone receptor-binding protein)
Gene: NCOA6

Interactor 2: CBP (Q92793)
CREB-binding protein (Histone lysine acetyltransferase CREBBP) (EC 2.3.1.48) (Protein lactyltransferas CREBBP) (EC 2.3.1.-) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-)
Gene: CREBBP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 0.60 0.669

The method score is based on:

Property Details
Experiments 10567404, 11158331, 10866662
Identification Methods two hybrid, pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003682 - chromatin binding
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005667 - transcription regulator complex
and 3 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Last updated: 15 Jul 2024