HitPredict

Interactor 1: CHD4 (Q14839)
Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12) (ATP-dependent helicase CHD4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta)
Gene: CHD4

Interactor 2: PHIP (Q8WWQ0)
PH-interacting protein (PHIP) (DDB1- and CUL4-associated factor 14) (IRS-1 PH domain-binding protein) (WD repeat-containing protein 11)
Gene: PHIP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29089422
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Bromodomain~PHD
Common GO terms	GO:0005634 - nucleus GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1912 Hs			1 1821
+	Hs
		1255033 CHD5_HUMAN (86-1909): 0: 1584: 71.18		PHIP_HUMAN (1-1821): 0: 1502: 100.00
+	Hs
		229448 SMCA5_HUMAN (578-1624): 0: 791: 26.01		PHIP_HUMAN (1-1821): 0: 1502: 100.00
+	Hs
		1016277 CHD4_HUMAN (1-1912): 0: 1719: 100.00		TBL3_HUMAN (7-495): 2.68e-90: 315: 14.31
+	Dm
		332801 CHDM_DROME (1-1904): 0: 1364: 50.85		Q8SX63_DROME (497-1685): 0: 608: 32.81
+	Hs
		903234 CHD4_HUMAN (1-1912): 0: 1719: 100.00		WDR5_HUMAN (352-664): 2.63e-65: 227: 16.62
+	Hs
		1059779 CHD4_HUMAN (1-1912): 0: 1719: 100.00		FBXW7_HUMAN (294-657): 3.51e-56: 211: 17.33
+	Hs
		1016272 CHD3_HUMAN (23-1905): 0: 1595: 66.89		TBL3_HUMAN (7-495): 2.68e-90: 315: 14.31
+	Hs
		1059704 CHD4_HUMAN (1-1912): 0: 1719: 100.00		PB1_HUMAN (1116-1652): 2.52e-41: 169: 15.22
+	Hs
		197020 CHD4_HUMAN (1-1912): 0: 1719: 100.00		PRP4_HUMAN (160-494): 2.06e-16: 86.7: 25.35
+	Hs
		1018633 CHD3_HUMAN (23-1905): 0: 1595: 66.89		SNR40_HUMAN (355-666): 5.05e-55: 198: 13.23
+	Hs
		1018557 CHD3_HUMAN (23-1905): 0: 1595: 66.89		PB1_HUMAN (1116-1652): 2.52e-41: 169: 15.22
+	Hs
		197011 CHD3_HUMAN (23-1905): 0: 1595: 66.89		PRP4_HUMAN (160-494): 2.06e-16: 86.7: 25.35
+	Hs
		1018714 CHD3_HUMAN (23-1905): 0: 1595: 66.89		NLE1_HUMAN (1-79): 1.4e-13: 77.6: 12.66
+	Hs
		1254435 CHD6_HUMAN (279-1685): 0: 782: 24.76		FBXW7_HUMAN (294-657): 3.51e-56: 211: 17.33
+	Hs
		658714 SMCA1_HUMAN (617-1597): 0: 779: 27.44		FBXW7_HUMAN (294-657): 3.51e-56: 211: 17.33
+	Hs
		903535 CHD8_HUMAN (489-1678): 0: 752: 28.31		WDR5_HUMAN (352-664): 2.63e-65: 227: 16.62
+	Hs
		658715 SMCA1_HUMAN (617-1597): 0: 779: 27.44		SNR40_HUMAN (355-666): 5.05e-55: 198: 13.23
+	Hs
		1199209 CHD7_HUMAN (3-1678): 0: 805: 23.02		PB1_HUMAN (1116-1652): 2.52e-41: 169: 15.22
+	Sc
		697375 CHD1_YEAST (515-1383): 0: 777: 35.17		BDF1_YEAST (1262-1490): 1.35e-23: 110: 20.78
+	Sc
		697383 CHD1_YEAST (515-1383): 0: 777: 35.17		TAF5_YEAST (181-311): 6.96e-09: 63.2: 32.58