HitPredict

Interactor 1: DHSO2 (Q07786)
Sorbitol dehydrogenase 2 (SDH 2) (EC 1.1.1.-) (Polyol dehydrogenase) (Xylitol dehydrogenase) (EC 1.1.1.9)
Gene: SOR2

Interactor 2: DHSO2 (Q07786)
Sorbitol dehydrogenase 2 (SDH 2) (EC 1.1.1.-) (Polyol dehydrogenase) (Xylitol dehydrogenase) (EC 1.1.1.9)
Gene: SOR2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	1.00	0.656

Property	Details
Experiments	10688190
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	ADH_N~ADH_N, ADH_N~ADH_zinc_N, ADH_zinc_N~ADH_zinc_N
Common GO terms	GO:0003939 - L-iditol 2-dehydrogenase (NAD+) activity GO:0006062 - sorbitol catabolic process GO:0008270 - zinc ion binding GO:0019318 - hexose metabolic process GO:0046526 - D-xylulose reductase activity
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 357 Sc			1 357
+	Sc
		771742 DHSO1_YEAST (1-357): 6.5e-125: 365: 99.72		DHSO2_YEAST (1-357): 1.66e-124: 363: 100.00
+	Ce
		1170363 Q21702_CAEEL (1-355): 1.79e-112: 333: 40.56		Q21702_CAEEL (1-355): 1.79e-112: 333: 40.56
+	Hs
		1492075 V9HW89_HUMAN (2-356): 1.29e-111: 331: 40.85		V9HW89_HUMAN (2-356): 1.29e-111: 331: 40.85
+	Hs
		1027328 DHSO_HUMAN (2-356): 5.71e-111: 329: 40.56		DHSO_HUMAN (2-356): 5.71e-111: 329: 40.56
+	Ce
		1170364 Q21702_CAEEL (1-355): 1.79e-112: 333: 40.56		Q21703_CAEEL (1-355): 1.48e-103: 310: 38.59
+	Dm
		355752 O96299_DROME (1-355): 2.28e-106: 317: 43.66		O97479_DROME (6-355): 1.08e-105: 316: 44.57
+	At
		443575 ADH1_ARATH (5-355): 4.13e-103: 310: 23.22		ADH1_ARATH (5-355): 4.13e-103: 310: 23.22
+	Hs
		548848 ADHX_HUMAN (4-355): 1.82e-101: 305: 22.90		ADHX_HUMAN (4-355): 1.82e-101: 305: 22.90
+	Sp
		785776 DHSO_SCHPO (1-357): 2.41e-101: 304: 46.94		DHSO_SCHPO (1-357): 2.41e-101: 304: 46.94
+	Hs
		358043 ADH1A_HUMAN (4-354): 2e-99: 300: 25.33		ADH1B_HUMAN (4-353): 2.62e-99: 300: 24.60
+	Hs
		358040 ADH1B_HUMAN (4-353): 2.62e-99: 300: 24.60		ADH1G_HUMAN (4-353): 1.06e-97: 296: 24.87
+	Ph
		237483 TDH_PYRHO (1-352): 1.24e-98: 297: 27.04		TDH_PYRHO (1-352): 1.24e-98: 297: 27.04
+	Sc
		452607 ADH3_YEAST (1-355): 8.62e-98: 296: 21.73		ADH3_YEAST (1-355): 8.62e-98: 296: 21.73
+	Sc
		358083 ADH3_YEAST (1-355): 8.62e-98: 296: 21.73		ADH1_YEAST (1-355): 3.1e-93: 283: 22.01
+	At
		1319955 ADHL6_ARATH (4-357): 8.19e-95: 289: 21.99		ADHL6_ARATH (4-357): 8.19e-95: 289: 21.99