HitPredict

Interactor 1: ZN169 (Q14929)
Zinc finger protein 169
Gene: ZNF169

Interactor 2: HIC2 (Q96JB3)
Hypermethylated in cancer 2 protein (Hic-2) (HIC1-related gene on chromosome 22 protein) (Hic-3) (Zinc finger and BTB domain-containing protein 30)
Gene: HIC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	zf-C2H2~zf-C2H2
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 603 Hs			1 615
+	Hs
		565101 ZNF7_HUMAN (11-594): 0: 679: 34.06		ZNF71_HUMAN (173-614): 3.39e-138: 413: 19.56
+	Hs
		563267 ZN708_HUMAN (11-601): 0: 716: 34.86		ZN543_HUMAN (67-404): 4.35e-73: 247: 9.15
+	Hs
		1060261 ZN169_HUMAN (1-603): 0: 719: 100.00		ZN184_HUMAN (65-386): 4.47e-67: 234: 7.43
+	Hs
		563279 ZNF7_HUMAN (11-594): 0: 679: 34.06		ZNF16_HUMAN (63-418): 2.16e-78: 263: 8.68
+	Hs
		1060269 ZN169_HUMAN (1-603): 0: 719: 100.00		ZN629_HUMAN (106-613): 1.29e-54: 201: 13.17
+	Hs
		885469 ZN169_HUMAN (1-603): 0: 719: 100.00		ZN121_HUMAN (438-612): 6.42e-25: 108: 33.14
+	Hs
		970660 ZN169_HUMAN (1-603): 0: 719: 100.00		ZNF45_HUMAN (515-615): 7.13e-22: 102: 29.70
+	Hs
		1060246 ZN169_HUMAN (1-603): 0: 719: 100.00		ZKSC8_HUMAN (272-424): 7.93e-19: 92.1: 13.64
+	Hs
		563270 ZN708_HUMAN (11-601): 0: 716: 34.86		ZKSC8_HUMAN (272-424): 7.93e-19: 92.1: 13.64
+	Hs
		977956 ZN169_HUMAN (1-603): 0: 719: 100.00		ZNF92_HUMAN (256-459): 3.24e-14: 77.8: 10.24
+	Hs
		1060263 ZN169_HUMAN (1-603): 0: 719: 100.00		GZF1_HUMAN (296-443): 5.35e-13: 74: 8.33
+	Hs
		1343989 ZNF71_HUMAN (218-509): 6.88e-97: 306: 51.71		ZNF71_HUMAN (173-614): 3.39e-138: 413: 19.56
+	Hs
		1169142 ZNF71_HUMAN (218-509): 6.88e-97: 306: 51.71		ZFP2_HUMAN (183-614): 1.15e-135: 406: 19.77
+	Hs
		1343651 PRDM9_HUMAN (86-596): 2.86e-163: 490: 51.89		PRDM9_HUMAN (107-367): 6.73e-23: 105: 9.92
+	Hs
		1305550 ZNF71_HUMAN (218-509): 6.88e-97: 306: 51.71		ZN184_HUMAN (65-386): 4.47e-67: 234: 7.43
+	Hs
		1239558 ZNF71_HUMAN (218-509): 6.88e-97: 306: 51.71		ZFP62_HUMAN (67-404): 1.26e-59: 216: 9.94
+	Mm
		990976 ZSCA2_MOUSE (258-596): 2.08e-103: 327: 50.74		S4R1L6_MOUSE (389-586): 6.46e-21: 99.4: 32.68
+	Mm
		50524 ZSCA2_MOUSE (258-596): 2.08e-103: 327: 50.74		A1L357_MOUSE (389-586): 1.16e-20: 97.8: 32.68
+	Hs
		240854 ZNF71_HUMAN (218-509): 6.88e-97: 306: 51.71		Z354A_HUMAN (501-612): 4.15e-14: 77.4: 35.71
+	Hs
		1328436 ZNF71_HUMAN (218-509): 6.88e-97: 306: 51.71		GZF1_HUMAN (296-443): 5.35e-13: 74: 8.33