Download interactions: TXT MITAB-2.5
| Interaction | Interactor | Experiments | Homologs | Category | Interaction Score |
Confidence |
|---|---|---|---|---|---|---|
|
BECN1
Beclin-1 |
54 |
8 |
Small-scale |
0.996 | High |
|
|
BAX
Apoptosis regulator BAX |
25 |
17 |
Small-scale |
0.990 | High |
|
|
B2L11
Bcl-2-like protein 11 |
18 |
17 |
Small-scale |
0.987 | High |
|
|
BAD
Bcl2-associated agonist of cell death |
12 |
8 |
Small-scale |
0.982 | High |
|
|
P53
Cellular tumor antigen p53 |
8 |
9 |
Small-scale |
0.975 | High |
|
|
BID
BH3-interacting domain death agonist |
8 |
10 |
Small-scale |
0.963 | High |
|
|
B2CL1
Bcl-2-like protein 1 |
6 |
17 |
Small-scale |
0.946 | High |
|
|
BAK
Bcl-2 homologous antagonist/killer |
6 |
17 |
Small-scale |
0.930 | High |
|
|
BBC3
Bcl-2-binding component 3, isoforms 1/2 |
5 |
7 |
Small-scale |
0.915 | High |
|
|
APR
Phorbol-12-myristate-13-acetate-induced protein 1 |
3 |
7 |
Small-scale |
0.861 | High |
|
|
BCL2
Apoptosis regulator Bcl-2 |
3 |
17 |
Small-scale |
0.847 | High |
|
|
ASPP2
Apoptosis-stimulating of p53 protein 2 |
2 |
3 |
Small-scale |
0.839 | High |
|
|
BMF
Bcl-2-modifying factor |
3 |
8 |
Small-scale |
0.814 | High |
|
|
NLRP1
NACHT, LRR and PYD domains-containing protein 1 |
2 |
2 |
Small-scale |
0.812 | High |
|
|
PRKN
E3 ubiquitin-protein ligase parkin |
2 |
7 |
Small-scale |
0.806 | High |
|
|
BAG1
BAG family molecular chaperone regulator 1 |
2 |
1 |
Small-scale |
0.757 | High |
|
|
FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8 |
7 |
2 |
Small-scale |
0.756 | High |
|
|
B2L10
Bcl-2-like protein 10 |
2 |
4 |
Small-scale |
0.754 | High |
|
|
BIK
Bcl-2-interacting killer |
11 |
6 |
Small-scale |
0.754 | High |
|
|
BAG6
Large proline-rich protein BAG6 |
1 |
4 |
Small-scale |
0.724 | High |
|
|
NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1 |
3 |
8 |
Small-scale |
0.692 | High |
|
|
BBC3B
Bcl-2-binding component 3, isoforms 3/4 |
4 |
5 |
Small-scale |
0.683 | High |
|
|
BNIP3
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 |
4 |
5 |
Small-scale |
0.674 | High |
|
|
RAF1
RAF proto-oncogene serine/threonine-protein kinase |
3 |
3 |
Small-scale |
0.674 | High |
|
|
PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform |
2 |
11 |
Small-scale |
0.660 | High |
|
|
ANKL2
Ankyrin repeat and LEM domain-containing protein 2 |
1 |
0 |
High-throughput |
0.656 | High |
|
|
BNIP2
BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 |
3 |
3 |
Small-scale |
0.651 | High |
|
|
CDK1
Cyclin-dependent kinase 1 |
3 |
5 |
Small-scale |
0.646 | High |
|
|
BAP31
B-cell receptor-associated protein 31 |
2 |
1 |
Small-scale |
0.641 | High |
|
|
ITPR1
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 |
2 |
5 |
Small-scale |
0.634 | High |
|
|
SODC
Superoxide dismutase [Cu-Zn] |
2 |
1 |
Small-scale |
0.634 | High |
|
|
PSN1
Presenilin-1 |
2 |
4 |
Small-scale |
0.620 | High |
|
|
CASP8
Caspase-8 |
2 |
8 |
Small-scale |
0.620 | High |
|
|
RAD9A
Cell cycle checkpoint control protein RAD9A |
2 |
2 |
Small-scale |
0.620 | High |
|
|
RTN4
Reticulon-4 |
2 |
3 |
Small-scale |
0.620 | High |
|
|
MDM4
Protein Mdm4 |
2 |
1 |
Small-scale |
0.611 | High |
|
|
BI1
Bax inhibitor 1 |
2 |
4 |
Small-scale |
0.611 | High |
|
|
HRK
Activator of apoptosis harakiri |
2 |
4 |
Small-scale |
0.605 | High |
|
|
MK01
Mitogen-activated protein kinase 1 |
1 |
2 |
Small-scale |
0.604 | High |
|
|
BNI3L
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like |
2 |
5 |
Small-scale |
0.595 | High |
|
|
SQSTM
Sequestosome-1 |
2 |
1 |
Small-scale |
0.595 | High |
|
|
MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1 |
1 |
16 |
Small-scale |
0.590 | High |
|
|
CEBPB
CCAAT/enhancer-binding protein beta |
2 |
4 |
Small-scale |
0.584 | High |
|
|
PP2BA
Protein phosphatase 3 catalytic subunit alpha |
2 |
13 |
Small-scale |
0.584 | High |
|
|
HIF1A
Hypoxia-inducible factor 1-alpha |
2 |
5 |
Small-scale |
0.584 | High |
|
|
AMRA1
Activating molecule in BECN1-regulated autophagy protein 1 |
1 |
5 |
Small-scale |
0.579 | High |
|
|
CISD2
CDGSH iron-sulfur domain-containing protein 2 |
1 |
1 |
Small-scale |
0.578 | High |
|
|
TOM20
Mitochondrial import receptor subunit TOM20 homolog |
2 |
0 |
Small-scale |
0.577 | High |
|
|
PPID
Peptidyl-prolyl cis-trans isomerase D |
1 |
2 |
Small-scale |
0.573 | High |
|
|
BRCA1
Breast cancer type 1 susceptibility protein |
1 |
4 |
Small-scale |
0.561 | High |
|
|
PPARA
Peroxisome proliferator-activated receptor alpha |
1 |
5 |
Small-scale |
0.561 | High |
|
|
HS90A
Heat shock protein HSP 90-alpha |
2 |
0 |
Small-scale |
0.559 | High |
|
|
SEPT4
Septin-4 |
1 |
1 |
Small-scale |
0.552 | High |
|
|
BNIPL
Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein |
1 |
3 |
Small-scale |
0.552 | High |
|
|
AVEN
Cell death regulator Aven |
1 |
1 |
Small-scale |
0.552 | High |
|
|
BFAR
Bifunctional apoptosis regulator |
1 |
5 |
Small-scale |
0.552 | High |
|
|
MK08
Mitogen-activated protein kinase 8 |
1 |
13 |
Small-scale |
0.550 | High |
|
|
SMN
Survival motor neuron protein |
1 |
0 |
Small-scale |
0.549 | High |
|
|
SPHK2
Sphingosine kinase 2 |
1 |
0 |
Small-scale |
0.537 | High |
|
|
XIAP
E3 ubiquitin-protein ligase XIAP |
1 |
1 |
Small-scale |
0.536 | High |
|
|
RGPD2
RANBP2-like and GRIP domain-containing protein 2 |
1 |
1 |
High-throughput |
0.536 | High |
|
|
ABCD1
ATP-binding cassette sub-family D member 1 |
1 |
1 |
High-throughput |
0.536 | High |
|
|
TAP1
Antigen peptide transporter 1 |
1 |
1 |
High-throughput |
0.536 | High |
|
|
MBRL
Membralin |
1 |
1 |
High-throughput |
0.536 | High |
|
|
PMYT1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase |
1 |
5 |
High-throughput |
0.536 | High |
|
|
MFF
Mitochondrial fission factor |
1 |
1 |
High-throughput |
0.536 | High |
|
|
GHITM
Growth hormone-inducible transmembrane protein |
1 |
4 |
High-throughput |
0.536 | High |
|
|
SIVA
Apoptosis regulatory protein Siva |
1 |
2 |
Small-scale |
0.527 | High |
|
|
VDAC1
Non-selective voltage-gated ion channel VDAC1 |
1 |
8 |
Small-scale |
0.515 | High |
|
|
PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit |
1 |
11 |
High-throughput |
0.515 | High |
|
|
PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit |
1 |
11 |
High-throughput |
0.515 | High |
|
|
PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit |
1 |
11 |
High-throughput |
0.515 | High |
|
|
SPNS1
Protein spinster homolog 1 |
1 |
1 |
Small-scale |
0.515 | High |
|
|
A4
Amyloid-beta precursor protein |
1 |
1 |
High-throughput |
0.515 | High |
|
|
CAN2
Calpain-2 catalytic subunit |
1 |
0 |
Small-scale |
0.513 | High |
|
|
MDR1
ATP-dependent translocase ABCB1 |
1 |
0 |
High-throughput |
0.513 | High |
|
|
MTHR
Methylenetetrahydrofolate reductase |
1 |
0 |
High-throughput |
0.513 | High |
|
|
PEX3
Peroxisomal biogenesis factor 3 |
1 |
0 |
High-throughput |
0.513 | High |
|
|
ACBD5
Acyl-CoA-binding domain-containing protein 5 |
1 |
0 |
High-throughput |
0.513 | High |
|
|
XXLT1
Xyloside xylosyltransferase 1 |
1 |
0 |
High-throughput |
0.513 | High |
|
|
MTMR4
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR4 |
1 |
0 |
High-throughput |
0.513 | High |
|
|
B2L12
Bcl-2-like protein 12 |
1 |
2 |
Small-scale |
0.508 | High |
|
|
RRAS
Ras-related protein R-Ras |
1 |
7 |
Small-scale |
0.504 | High |
|
|
PARP1
Poly [ADP-ribose] polymerase 1 |
1 |
3 |
Small-scale |
0.501 | High |
|
|
CASP3
Caspase-3 |
1 |
8 |
Small-scale |
0.501 | High |
|
|
PP2BC
Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform |
1 |
14 |
Small-scale |
0.501 | High |
|
|
BLK
Tyrosine-protein kinase Blk |
1 |
3 |
Small-scale |
0.501 | High |
|
|
CANB1
Calcineurin subunit B type 1 |
1 |
1 |
Small-scale |
0.501 | High |
|
|
SEC20
Vesicle transport protein SEC20 |
1 |
1 |
Small-scale |
0.501 | High |
|
|
RN183
E3 ubiquitin-protein ligase RNF183 |
1 |
1 |
Small-scale |
0.501 | High |
|
|
BCLF1
Bcl-2-associated transcription factor 1 |
1 |
1 |
Small-scale |
0.500 | High |
|
|
NMT2
Glycylpeptide N-tetradecanoyltransferase 2 |
1 |
0 |
Small-scale |
0.493 | High |
|
|
AP2A
Transcription factor AP-2-alpha |
1 |
0 |
Small-scale |
0.493 | High |
|
|
GLT10
Polypeptide N-acetylgalactosaminyltransferase 10 |
1 |
1 |
High-throughput |
0.489 | High |
|
|
HNRPD
Heterogeneous nuclear ribonucleoprotein D0 |
1 |
1 |
Small-scale |
0.481 | High |
|
|
BECN2
Beclin-2 |
1 |
8 |
Small-scale |
0.479 | High |
|
|
IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta |
1 |
3 |
Small-scale |
0.479 | High |
|
|
IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha |
1 |
3 |
Small-scale |
0.479 | High |
|
|
KLF4
Krueppel-like factor 4 |
1 |
1 |
Small-scale |
0.479 | High |
|
|
ATG12
Ubiquitin-like protein ATG12 |
1 |
1 |
Small-scale |
0.479 | High |
|
|
RTN3
Reticulon-3 |
1 |
3 |
Small-scale |
0.479 | High |
|
|
BAG3
BAG family molecular chaperone regulator 3 |
1 |
5 |
Small-scale |
0.479 | High |
|
|
MYC
Myc proto-oncogene protein |
1 |
1 |
Small-scale |
0.479 | High |
|
|
RASK
GTPase KRas |
1 |
6 |
Small-scale |
0.479 | High |
|
|
CRYAB
Alpha-crystallin B chain |
1 |
6 |
Small-scale |
0.479 | High |
|
|
GCR
Glucocorticoid receptor |
1 |
6 |
Small-scale |
0.479 | High |
|
|
CDK2
Cyclin-dependent kinase 2 |
1 |
5 |
Small-scale |
0.479 | High |
|
|
PML
Protein PML |
1 |
1 |
Small-scale |
0.479 | High |
|
|
IRS1
Insulin receptor substrate 1 |
1 |
3 |
Small-scale |
0.479 | High |
|
|
PSN2
Presenilin-2 |
1 |
4 |
Small-scale |
0.479 | High |
|
|
SPB8
Serpin B8 |
1 |
2 |
Small-scale |
0.479 | High |
|
|
DYL1
Dynein light chain 1, cytoplasmic |
1 |
4 |
Small-scale |
0.479 | High |
|
|
UBC9
SUMO-conjugating enzyme UBC9 |
1 |
2 |
Small-scale |
0.479 | High |
|
|
PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
1 |
2 |
Small-scale |
0.479 | High |
|
|
CUL4A
Cullin-4A |
1 |
2 |
High-throughput |
0.479 | High |
|
|
KEAP1
Kelch-like ECH-associated protein 1 |
1 |
1 |
Small-scale |
0.479 | High |
|
|
ITPR3
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3 |
1 |
5 |
Small-scale |
0.479 | High |
|
|
BLID
BH3-like motif-containing cell death inducer |
1 |
1 |
Small-scale |
0.479 | High |
|
|
PRUN2
Protein prune homolog 2 |
1 |
3 |
Small-scale |
0.479 | High |
|
|
NR4A3
Nuclear receptor subfamily 4 group A member 3 |
1 |
5 |
Small-scale |
0.479 | High |
|
|
AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 |
1 |
1 |
Small-scale |
0.479 | High |
|
|
MOAP1
Modulator of apoptosis 1 |
1 |
2 |
Small-scale |
0.479 | High |
|
|
LFG2
Protein lifeguard 2 |
1 |
4 |
Small-scale |
0.479 | High |
|
|
IRS2
Insulin receptor substrate 2 |
1 |
4 |
Small-scale |
0.479 | High |
|
|
NEMO
NF-kappa-B essential modulator |
1 |
2 |
Small-scale |
0.479 | High |
|
|
MEX3D
RNA-binding protein MEX3D |
1 |
0 |
Small-scale |
0.460 | High |
|
|
RB
Retinoblastoma-associated protein |
1 |
0 |
Small-scale |
0.458 | High |
|
|
GLI2
Zinc finger protein GLI2 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
LEG3
Galectin-3 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
METK2
S-adenosylmethionine synthase isoform type-2 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial |
1 |
0 |
Small-scale |
0.458 | High |
|
|
2A5A
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform |
1 |
0 |
Small-scale |
0.458 | High |
|
|
PTPA
Serine/threonine-protein phosphatase 2A activator |
1 |
0 |
Small-scale |
0.458 | High |
|
|
TPIP1
p53-regulated apoptosis-inducing protein 1 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
ITM2B
Integral membrane protein 2B |
1 |
0 |
Small-scale |
0.458 | High |
|
|
PPIF
Peptidyl-prolyl cis-trans isomerase F, mitochondrial |
1 |
3 |
Small-scale |
0.457 | High |
|
|
VRK2
Serine/threonine-protein kinase VRK2 |
1 |
3 |
Small-scale |
0.457 | High |
|
|
LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2 |
1 |
1 |
Small-scale |
0.445 | High |
|
|
BOP
Protein Bop |
1 |
6 |
Small-scale |
0.445 | High |
|
|
GIMA5
GTPase IMAP family member 5 |
1 |
5 |
Small-scale |
0.437 | High |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
