Protein: MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Bcl-2-related protein EAT/mcl1)

Gene: MCL1
Organism: Mus musculus
Interactions: 22
UniProt ID: P97287

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1021080

APR
Phorbol-12-myristate-13-acetate-induced protein 1

5

7

Small-scale

0.932

High

236680

B2L11
Bcl-2-like protein 11

5

16

Small-scale

0.920

High

148125

BAK
Bcl-2 homologous antagonist/killer

1

17

Small-scale

0.692

High

1021079

BBC3
Bcl-2-binding component 3

1

7

Small-scale

0.692

High

509031

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]

1

2

High-throughput

0.647

High

1000440

BID
BH3-interacting domain death agonist

1

10

Small-scale

0.647

High

1021078

BMF
Bcl-2-modifying factor

1

6

Small-scale

0.647

High

1021073

TRI17
E3 ubiquitin-protein ligase TRIM17

1

3

Small-scale

0.512

High

1021077

MK08
Mitogen-activated protein kinase 8

1

13

Small-scale

0.501

High

1021084

GSK3B
Glycogen synthase kinase-3 beta

1

9

Small-scale

0.501

High

1021070

HIF3A
Hypoxia-inducible factor 3-alpha

1

5

Small-scale

0.479

High

1021071

STING
Stimulator of interferon genes protein

1

1

High-throughput

0.479

High

1021072

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

3

Small-scale

0.479

High

1021076

FBXW7
F-box/WD repeat-containing protein 7

1

4

Small-scale

0.479

High

1021081

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

2

Small-scale

0.479

High

1021082

SKP1
S-phase kinase-associated protein 1

1

1

Small-scale

0.479

High

984046

RBX1
E3 ubiquitin-protein ligase RBX1

1

0

Small-scale

0.458

High

1021074

FACD2
Fanconi anemia group D2 protein homolog

1

0

High-throughput

0.458

High

398325

CFAD
Complement factor D

1

2

High-throughput

0.437

High

1021083

CUL1
Cullin-1

1

2

Small-scale

0.437

High

46507

SIM43
Small integral membrane protein 43

1

0

High-throughput

0.249

Low

1021075

FNDC5
Fibronectin type III domain-containing protein 5

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025