Interactor 1: DPOE1 (Q07864)
DNA polymerase epsilon catalytic subunit A (EC 2.7.7.7) (3'-5' exodeoxyribonuclease) (EC 3.1.11.-) (DNA polymerase II subunit A)
Gene: POLE

Interactor 2: RTEL1 (Q9NZ71)
Regulator of telomere elongation helicase 1 (EC 5.6.2.-) (Novel helicase-like)
Gene: RTEL1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 39039288
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0051539 - 4 iron, 4 sulfur cluster binding
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 2286
Hs

1 1219
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025