Protein: CHL1
ATP-dependent DNA helicase CHL1 (EC 5.6.2.3) (Chromosome loss protein 1) (Chromosome transmission fidelity protein 1) (DNA 5'-3' helicase CHL1)

Gene: CHL1
Organism: Saccharomyces cerevisiae S288C
Interactions: 31
UniProt ID: P22516

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0003677 - DNA binding
GO:0003678 - DNA helicase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

392249

HSP82
ATP-dependent molecular chaperone HSP82

3

2

Small-scale

0.670

High

649559

SCC1
Sister chromatid cohesion protein 1

3

0

Small-scale

0.613

High

649545

ECO1
N-acetyltransferase ECO1

1

0

Small-scale

0.554

High

649555

CTF4
DNA polymerase alpha-binding protein

1

1

Small-scale

0.536

High

649540

ORC2
Origin recognition complex subunit 2

1

0

Small-scale

0.529

High

649552

ORC3
Origin recognition complex subunit 3

1

0

Small-scale

0.529

High

649549

TOF1
Topoisomerase 1-associated factor 1

1

1

Small-scale

0.501

High

649535

MRC1
Mediator of replication checkpoint protein 1

1

0

Small-scale

0.480

High

649541

SMC1
Structural maintenance of chromosomes protein 1

1

0

Small-scale

0.480

High

649558

CSM3
Chromosome segregation in meiosis protein 3

1

0

Small-scale

0.480

High

649536

FEN1
Flap endonuclease 1

1

3

Small-scale

0.479

High

649537

MCM2
DNA replication licensing factor MCM2

1

1

Small-scale

0.479

High

649551

ORC1
Origin recognition complex subunit 1

1

1

Small-scale

0.479

High

649539

CBF3A
Centromere DNA-binding protein complex CBF3 subunit A

1

0

Small-scale

0.460

High

649543

ORC6
Origin recognition complex subunit 6

1

0

Small-scale

0.460

High

649546

CDT1
Cell division cycle protein CDT1

1

0

Small-scale

0.460

High

649553

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

0

High-throughput

0.460

High

649547

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

649548

SSU72
RNA polymerase II subunit A C-terminal domain phosphatase SSU72

1

0

Small-scale

0.458

High

649554

PTA1
Pre-tRNA-processing protein PTA1

1

0

Small-scale

0.458

High

649557

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

649556

UBC7
Ubiquitin-conjugating enzyme E2 7

1

1

High-throughput

0.457

High

525950

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.445

High

543849

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.445

High

649534

MAS5
Mitochondrial protein import protein MAS5

1

4

High-throughput

0.445

High

649542

SSZ1
Ribosome-associated complex subunit SSZ1

1

1

High-throughput

0.445

High

649544

SSB2
Ribosome-associated molecular chaperone SSB2

1

4

High-throughput

0.445

High

561287

DPOLA
DNA polymerase alpha catalytic subunit A

1

1

Small-scale

0.437

High

649538

HS104
Heat shock protein 104

1

0

High-throughput

0.426

High

587285

ABP1
Actin-binding protein

1

0

High-throughput

0.282

High

649550

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025