HitPredict

Interactor 1: IMB1 (Q14974)
Importin subunit beta-1 (Importin-90) (Karyopherin subunit beta-1) (Nuclear factor p97) (Pore targeting complex 97 kDa subunit) (PTAC97)
Gene: KPNB1

Interactor 2: NUP54 (Q7Z3B4)
Nucleoporin p54 (54 kDa nucleoporin)
Gene: NUP54

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	11266456
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005635 - nuclear envelope GO:0005643 - nuclear pore GO:0006607 - NLS-bearing protein import into nucleus GO:0031965 - nuclear membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 876 Hs			1 507
+	Xl
		853821 IMB_XENLA (1-876): 0: 631: 94.52		Q6PAY1_XENLA (1-507): 1.37e-148: 436: 74.07
+	Hs
		727254 IMB1_HUMAN (1-876): 0: 635: 100.00		NU214_HUMAN (7-179): 1.39e-17: 88.5: 16.04
+	Hs
		857978 IMB1_HUMAN (1-876): 0: 635: 100.00		NUP98_HUMAN (2-257): 4.92e-12: 70.8: 15.44
+	Xl
		853820 IMB_XENLA (1-876): 0: 631: 94.52		Q6DCP4_XENLA (4-289): 7.38e-13: 73.1: 17.35
+	Sc
		830681 IMB1_YEAST (2-871): 8.02e-148: 459: 33.33		NU145_YEAST (2-422): 1.95e-69: 243: 15.68
+	Hs
		1060869 IMB1_HUMAN (1-876): 0: 635: 100.00		P121A_HUMAN (2-189): 1.69e-09: 62.7: 18.78
+	Sc
		823006 IMB1_YEAST (2-871): 8.02e-148: 459: 33.33		NUP57_YEAST (3-489): 1.88e-59: 206: 18.52
+	Sc
		746520 IMB2_YEAST (1-758): 5.92e-112: 366: 13.61		NU145_YEAST (2-422): 1.95e-69: 243: 15.68
+	Sc
		746518 IMB2_YEAST (1-758): 5.92e-112: 366: 13.61		NUP57_YEAST (3-489): 1.88e-59: 206: 18.52
+	Sc
		971907 IMB1_YEAST (2-871): 8.02e-148: 459: 33.33		NU116_YEAST (5-265): 1.36e-12: 72.3: 13.51
+	Sc
		969363 IMB1_YEAST (2-871): 8.02e-148: 459: 33.33		NUP49_YEAST (6-267): 5.59e-11: 66.6: 11.28
+	Sc
		774378 IMB1_YEAST (2-871): 8.02e-148: 459: 33.33		NU159_YEAST (44-283): 8.5e-10: 63.5: 10.36
+	Sc
		746534 IMB2_YEAST (1-758): 5.92e-112: 366: 13.61		NU116_YEAST (5-265): 1.36e-12: 72.3: 13.51
+	Sc
		746532 IMB2_YEAST (1-758): 5.92e-112: 366: 13.61		NUP49_YEAST (6-267): 5.59e-11: 66.6: 11.28
+	Ce
		1341732 Q9N5V3_CAEEL (2-825): 2.5e-88: 305: 12.90		Q9XWK3_CAEEL (11-206): 2.02e-12: 71.6: 19.62
+	Ce
		136533 Q9N5V3_CAEEL (2-825): 2.5e-88: 305: 12.90		O01576_CAEEL (23-252): 4.32e-12: 70.8: 9.75
+	Sc
		687967 IMB3_YEAST (3-831): 2.12e-34: 144: 16.29		NUP57_YEAST (3-489): 1.88e-59: 206: 18.52
+	Ce
		248203 O62333_CAEEL (452-750): 9.26e-66: 228: 21.07		Q9XWK3_CAEEL (11-206): 2.02e-12: 71.6: 19.62
+	Ce
		248198 O62333_CAEEL (452-750): 9.26e-66: 228: 21.07		Q21295_CAEEL (8-208): 8.74e-09: 60: 12.20
+	Sc
		687954 IMB3_YEAST (3-831): 2.12e-34: 144: 16.29		NU159_YEAST (44-283): 8.5e-10: 63.5: 10.36