Protein: KAT5
Histone acetyltransferase KAT5 (EC 2.3.1.48) (60 kDa Tat-interactive protein) (Tip60) (Histone acetyltransferase HTATIP) (Lysine acetyltransferase 5) (Protein 2-hydroxyisobutyryltransferase KAT5) (EC 2.3.1.-) (Protein acetyltransferase KAT5) (EC 2.3.1.-) (Protein crotonyltransferase KAT5) (EC 2.3.1.-) (Protein lactyltransferase KAT5) (EC 2.3.1.-)

Gene: KAT5
Organism: Mus musculus
Interactions: 75
UniProt ID: Q8CHK4

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000132 - establishment of mitotic spindle orientation
GO:0000724 - double-strand break repair via homologous recombination
GO:0000776 - kinetochore
GO:0000786 - nucleosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

953368

MO4L1
Mortality factor 4-like protein 1

2

11

Small-scale

0.737

High

1297679

EPC2
Enhancer of polycomb homolog 2

2

7

Small-scale

0.737

High

1298195

EPC1
Enhancer of polycomb homolog 1

2

7

Small-scale

0.737

High

1298631

ING3
Inhibitor of growth protein 3

2

15

Small-scale

0.737

High

1189391

H2AV
Histone H2A.V

1

14

Small-scale

0.618

High

1225799

H2B2B
Histone H2B type 2-B

1

20

Small-scale

0.618

High

1298629

KAT5
Histone acetyltransferase KAT5

1

12

Small-scale

0.618

High

1298623

EP400
E1A-binding protein p400

2

9

Small-scale

0.588

High

1298630

BRD8
Bromodomain-containing protein 8

2

14

Small-scale

0.588

High

1298642

DMAP1
DNA methyltransferase 1-associated protein 1

2

4

Small-scale

0.588

High

1021524

PITX2
Pituitary homeobox 2

2

4

Small-scale

0.586

High

927913

ATX1
Ataxin-1

1

2

Small-scale

0.578

High

502204

H2AZ
Histone H2A.Z

1

14

Small-scale

0.575

High

949077

RUVB1
RuvB-like 1

2

9

Small-scale

0.571

High

953274

ACTB
Actin, cytoplasmic 1

2

11

Small-scale

0.571

High

993109

ACTG
Actin, cytoplasmic 2

2

11

Small-scale

0.571

High

1298647

ACL6A
Actin-like protein 6A

2

14

Small-scale

0.571

High

1021231

ETV6
Transcription factor ETV6

1

8

Small-scale

0.552

High

459934

RIR1
Ribonucleoside-diphosphate reductase large subunit

1

1

Small-scale

0.501

High

704113

MAX
Protein max

1

8

High-throughput

0.484

High

1283074

TRRAP
Transformation/transcription domain-associated protein

1

11

High-throughput

0.484

High

312399

MTR1L
Melatonin-related receptor

1

0

Small-scale

0.484

High

59533

SETX
Probable helicase senataxin

1

1

Small-scale

0.479

High

98014

ARI1B
AT-rich interactive domain-containing protein 1B

1

1

Small-scale

0.479

High

98342

E9QLK7
Transformation/transcription domain-associated protein

1

11

Small-scale

0.479

High

104755

TPR
Nucleoprotein TPR

1

2

Small-scale

0.479

High

148281

CLOCK
Circadian locomoter output cycles protein kaput

1

3

Small-scale

0.479

High

568898

DNMT1
DNA

1

2

Small-scale

0.479

High

854781

RAGP1
Ran GTPase-activating protein 1

1

2

Small-scale

0.479

High

866489

PA24A
Cytosolic phospholipase A2

1

3

Small-scale

0.479

High

973019

RS18
Small ribosomal subunit protein uS13

1

1

Small-scale

0.479

High

996580

ACTS
Actin, alpha skeletal muscle

1

10

Small-scale

0.479

High

997263

TBA1A
Tubulin alpha-1A chain

1

2

Small-scale

0.479

High

1180713

EAF6
Chromatin modification-related protein MEAF6

1

7

Small-scale

0.479

High

1187968

Q3SYK5
Tyrosine-protein kinase

1

1

Small-scale

0.479

High

1222560

HIF1A
Hypoxia-inducible factor 1-alpha

1

3

Small-scale

0.479

High

1223951

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

1

Small-scale

0.479

High

1224067

TIF1B
Transcription intermediary factor 1-beta

1

5

Small-scale

0.479

High

1224107

ATM
Serine-protein kinase ATM

1

11

Small-scale

0.479

High

1224227

VPS72
Vacuolar protein sorting-associated protein 72 homolog

1

1

Small-scale

0.479

High

1242749

MBTD1
MBT domain-containing protein 1

1

2

Small-scale

0.479

High

1297345

FLNA
Filamin-A

1

2

Small-scale

0.479

High

1298632

SFPQ
Splicing factor, proline- and glutamine-rich

1

5

Small-scale

0.479

High

1298634

STK38
Serine/threonine-protein kinase 38

1

2

Small-scale

0.479

High

1298636

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

5

Small-scale

0.479

High

1298637

FOXP3
Forkhead box protein P3

1

6

Small-scale

0.479

High

1298638

NONO
Non-POU domain-containing octamer-binding protein

1

5

Small-scale

0.479

High

1298639

YETS4
YEATS domain-containing protein 4

1

8

Small-scale

0.479

High

1298640

MRGBP
MRG/MORF4L-binding protein

1

1

Small-scale

0.479

High

1298644

Q9QXJ2
Signal transducer and activator of transcription

1

1

Small-scale

0.479

High

1298645

MO4L2
Mortality factor 4-like protein 2

1

10

Small-scale

0.479

High

1298646

RUVB2
RuvB-like 2

1

9

Small-scale

0.479

High

1298648

HDAC6
Protein deacetylase HDAC6

1

5

Small-scale

0.479

High

1298649

HNRPF
Heterogeneous nuclear ribonucleoprotein F

1

7

Small-scale

0.479

High

989271

HSP7C
Heat shock cognate 71 kDa protein

1

0

Small-scale

0.458

High

1023483

TBB5
Tubulin beta-5 chain

1

0

Small-scale

0.458

High

1135320

HDX
Highly divergent homeobox

1

0

Small-scale

0.458

High

1189981

TBRG1
Transforming growth factor beta regulator 1

1

0

Small-scale

0.458

High

1298641

LIMA1
LIM domain and actin-binding protein 1

1

0

Small-scale

0.458

High

1298643

FLII
Protein flightless-1 homolog

1

0

Small-scale

0.458

High

883828

CENPC
Centromere protein C

1

1

Small-scale

0.457

High

373701

MYC
Myc proto-oncogene protein

1

8

High-throughput

0.445

High

439042

LDHA
L-lactate dehydrogenase A chain

1

1

High-throughput

0.445

High

773337

FOXA2
Hepatocyte nuclear factor 3-beta

1

2

Small-scale

0.445

High

908491

HDGF
Hepatoma-derived growth factor

1

6

High-throughput

0.445

High

993451

ACTH
Actin, gamma-enteric smooth muscle

1

11

High-throughput

0.445

High

1204312

MEIKN
Meiosis-specific kinetochore protein

1

0

Small-scale

0.438

High

86361

B9EKJ1
Spectrin alpha chain, non-erythrocytic 1

1

1

Small-scale

0.437

High

1253366

Q6ZPV5
MKIAA1235 protein

1

1

Small-scale

0.437

High

1298635

LRRF2
Leucine-rich repeat flightless-interacting protein 2

1

3

Small-scale

0.437

High

1298633

CPIN1
Anamorsin

1

0

High-throughput

0.426

High

770501

RAB5C
Ras-related protein Rab-5C

1

0

Small-scale

0.249

Low

1296825

SUN2
SUN domain-containing protein 2

1

0

Small-scale

0.249

Low

1298147

Q8C839
Phosphatase PP2A regulatory subunit A/Splicing factor 3B subunit 1-like HEAT repeat domain-containing protein

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025