HitPredict

Interactor 1: NUMA1 (Q14980)
Nuclear mitotic apparatus protein 1 (Nuclear matrix protein-22) (NMP-22) (Nuclear mitotic apparatus protein) (NuMA protein) (SP-H antigen)
Gene: NUMA1

Interactor 2: H2A2B (Q8IUE6)
Histone H2A type 2-B (H2A-clustered histone 21)
Gene: H2AC21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0070062 - extracellular exosome
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 2115 Hs			1 130
+	Hs
		1061142 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		H2A2A_HUMAN (1-130): 5.07e-68: 202: 94.62
+	Hs
		1061198 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		H2A1C_HUMAN (1-130): 5.24e-68: 202: 95.39
+	Hs
		1061219 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		H2A1J_HUMAN (1-128): 6.6e-68: 202: 95.31
+	Hs
		391707 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		H2A1B_HUMAN (1-130): 1e-67: 202: 93.85
+	Hs
		594847 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		H2A1D_HUMAN (1-130): 9.47e-68: 202: 93.85
+	Hs
		555467 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		H2AX_HUMAN (1-123): 4.57e-66: 198: 95.94
+	Hs
		391578 MYH10_HUMAN (1281-2075): 5.26e-33: 142: 12.34		H2A1B_HUMAN (1-130): 1e-67: 202: 93.85
+	Hs
		1067434 EEA1_HUMAN (964-1838): 2.18e-28: 127: 12.15		H2A2A_HUMAN (1-130): 5.07e-68: 202: 94.62
+	Hs
		391713 EEA1_HUMAN (964-1838): 2.18e-28: 127: 12.15		H2A1B_HUMAN (1-130): 1e-67: 202: 93.85
+	Hs
		1067427 EEA1_HUMAN (964-1838): 2.18e-28: 127: 12.15		H2A2C_HUMAN (1-127): 3.2e-67: 200: 96.06
+	Hs
		728498 MYH11_HUMAN (1430-2076): 4.75e-22: 107: 8.41		H2A1C_HUMAN (1-130): 5.24e-68: 202: 95.39