HitPredict

Interactor 1: SRSF5 (Q13243)
Serine/arginine-rich splicing factor 5 (Delayed-early protein HRS) (Pre-mRNA-splicing factor SRP40) (Splicing factor, arginine/serine-rich 5)
Gene: SRSF5

Interactor 2: MDC1 (Q14676)
Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1)
Gene: MDC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 272 Hs			1 2089
+	Hs
		1060981 SRSF1_HUMAN (2-170): 6.58e-57: 184: 43.68		MDC1_HUMAN (1-2089): 0: 680: 100.00
+	Hs
		1098963 SRSF9_HUMAN (2-211): 1.48e-52: 172: 33.02		MDC1_HUMAN (1-2089): 0: 680: 100.00
+	Hs
		799031 SRSF1_HUMAN (2-170): 6.58e-57: 184: 43.68		BRCA1_HUMAN (405-2081): 8.49e-75: 279: 8.23
+	Hs
		854027 SRSF5_HUMAN (1-240): 2.61e-54: 178: 100.00		KI67_HUMAN (38-1926): 1.25e-69: 263: 9.54
+	Hs
		854014 SRSF4_HUMAN (5-265): 3.79e-51: 176: 53.64		KI67_HUMAN (38-1926): 1.25e-69: 263: 9.54
+	Hs
		854028 SRSF6_HUMAN (5-184): 1.34e-48: 165: 61.96		KI67_HUMAN (38-1926): 1.25e-69: 263: 9.54
+	Hs
		1061030 SRSF1_HUMAN (2-170): 6.58e-57: 184: 43.68		PAXI1_HUMAN (1814-2081): 2.33e-51: 201: 28.11
+	Hs
		1099130 SRSF5_HUMAN (1-240): 2.61e-54: 178: 100.00		PAXI1_HUMAN (1814-2081): 2.33e-51: 201: 28.11
+	Hs
		1062023 SRSF4_HUMAN (5-265): 3.79e-51: 176: 53.64		PAXI1_HUMAN (1814-2081): 2.33e-51: 201: 28.11
+	Hs
		1098989 SRSF9_HUMAN (2-211): 1.48e-52: 172: 33.02		PAXI1_HUMAN (1814-2081): 2.33e-51: 201: 28.11
+	Hs
		799067 PABP4_HUMAN (104-189): 2.67e-16: 80.1: 21.98		BRCA1_HUMAN (405-2081): 8.49e-75: 279: 8.23
+	Hs
		550155 PABP1_HUMAN (98-189): 8.49e-16: 79: 18.56		BRCA1_HUMAN (405-2081): 8.49e-75: 279: 8.23
+	Hs
		1061211 SRSF1_HUMAN (2-170): 6.58e-57: 184: 43.68		SRRM2_HUMAN (97-1940): 1.48e-24: 115: 8.27
+	Hs
		1099309 SRSF5_HUMAN (1-240): 2.61e-54: 178: 100.00		SRRM2_HUMAN (97-1940): 1.48e-24: 115: 8.27
+	Hs
		1062155 SRSF4_HUMAN (5-265): 3.79e-51: 176: 53.64		SRRM2_HUMAN (97-1940): 1.48e-24: 115: 8.27
+	Hs
		1099605 SRSF6_HUMAN (5-184): 1.34e-48: 165: 61.96		SRRM2_HUMAN (97-1940): 1.48e-24: 115: 8.27
+	Hs
		1099491 SRSF6_HUMAN (5-184): 1.34e-48: 165: 61.96		MINT_HUMAN (224-1896): 3.16e-16: 88.1: 11.94
+	Hs
		875649 PABP4_HUMAN (104-189): 2.67e-16: 80.1: 21.98		PRC2A_HUMAN (609-1919): 1.32e-13: 79.2: 9.07
+	Hs
		550171 PABP1_HUMAN (98-189): 8.49e-16: 79: 18.56		PRC2A_HUMAN (609-1919): 1.32e-13: 79.2: 9.07
+	Hs
		1102036 PABP4_HUMAN (104-189): 2.67e-16: 80.1: 21.98		TITIN_HUMAN (137-816): 5.64e-12: 74.2: 7.90