HitPredict

Interactor 1: NUMA1 (Q14980)
Nuclear mitotic apparatus protein 1 (Nuclear matrix protein-22) (NMP-22) (Nuclear mitotic apparatus protein) (NuMA protein) (SP-H antigen)
Gene: NUMA1

Interactor 2: ECT2 (Q9H8V3)
Protein ECT2 (Epithelial cell-transforming sequence 2 oncogene)
Gene: ECT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31586073, 22990118
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005813 - centrosome GO:0005829 - cytosol GO:0005938 - cell cortex and 1 others more... GO:0072686 - mitotic spindle
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 2115 Hs			1 914
+	Hs
		725023 MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		725246 MYH10_HUMAN (1281-2075): 5.26e-33: 142: 12.34		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		1068667 PLEC_HUMAN (45-1230): 3.46e-32: 140: 13.37		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		728517 MYH11_HUMAN (1430-2076): 4.75e-22: 107: 8.41		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		1273273 CP250_HUMAN (1-1659): 6.01e-59: 228: 13.08		ARHG2_HUMAN (249-775): 2e-83: 291: 15.02
+	Hs
		724913 MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62		ARG28_HUMAN (216-807): 7.17e-88: 309: 12.32
+	Hs
		1068638 PLEC_HUMAN (45-1230): 3.46e-32: 140: 13.37		FGD4_HUMAN (312-858): 1.12e-81: 281: 18.53
+	Hs
		50564 MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62		PKHG3_HUMAN (394-892): 2.49e-76: 273: 18.53
+	Hs
		1068677 PLEC_HUMAN (45-1230): 3.46e-32: 140: 13.37		ARHG4_HUMAN (350-880): 1.39e-79: 274: 17.20
+	Hs
		548710 PLEC_HUMAN (45-1230): 3.46e-32: 140: 13.37		VAV_HUMAN (390-707): 1.61e-76: 269: 21.82
+	Hs
		1068630 PLEC_HUMAN (45-1230): 3.46e-32: 140: 13.37		Q96D37_HUMAN (390-707): 1.05e-76: 268: 21.82
+	Hs
		724971 MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62		ARHGH_HUMAN (398-726): 8.05e-68: 249: 23.82
+	Hs
		1192498 CNTRL_HUMAN (3-811): 1.27e-16: 89.3: 11.29		ARHG2_HUMAN (249-775): 2e-83: 291: 15.02
+	Hs
		1356647 MYH13_HUMAN (6-516): 7.3e-15: 83.1: 10.66		PKHG1_HUMAN (367-887): 3.48e-78: 280: 16.79
+	Hs
		1021851 CP250_HUMAN (1-1659): 6.01e-59: 228: 13.08		ABR_HUMAN (463-641): 7.42e-16: 84.3: 30.27
+	Hs
		962561 PLEC_HUMAN (45-1230): 3.46e-32: 140: 13.37		ECT2L_HUMAN (453-721): 2.8e-23: 108: 28.93