HitPredict

Interactor 1: NUMA1 (Q14980)
Nuclear mitotic apparatus protein 1 (Nuclear matrix protein-22) (NMP-22) (Nuclear mitotic apparatus protein) (NuMA protein) (SP-H antigen)
Gene: NUMA1

Interactor 2: BRD7 (Q9NPI1)
Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1)
Gene: BRD7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016363 - nuclear matrix
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 2115 Hs			1 651
+	Hs
		876692 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		BRPF1_HUMAN (4-406): 3.3e-56: 208: 19.24
+	Hs
		319199 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		BRD1_HUMAN (22-393): 1.28e-54: 203: 20.05
+	Hs
		1061286 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		ATD2B_HUMAN (35-553): 3.74e-50: 190: 14.82
+	Hs
		998721 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		EP300_HUMAN (42-251): 3.1e-41: 164: 22.02
+	Hs
		1061186 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		PHIP_HUMAN (115-637): 1.3e-38: 155: 12.74
+	Hs
		631429 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		BRD2_HUMAN (115-424): 3.01e-33: 138: 15.39
+	Hs
		725030 MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62		BRD7_HUMAN (1-651): 1.84e-168: 498: 100.00
+	Hs
		319112 MYH6_HUMAN (1-883): 5.66e-32: 139: 13.37		BRD1_HUMAN (22-393): 1.28e-54: 203: 20.05
+	Hs
		724792 MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62		EP300_HUMAN (42-251): 3.1e-41: 164: 22.02
+	Hs
		725147 MYH10_HUMAN (1281-2075): 5.26e-33: 142: 12.34		EP300_HUMAN (42-251): 3.1e-41: 164: 22.02
+	Hs
		724946 MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62		CBP_HUMAN (25-238): 1.58e-39: 158: 23.11
+	Hs
		998727 EEA1_HUMAN (964-1838): 2.18e-28: 127: 12.15		EP300_HUMAN (42-251): 3.1e-41: 164: 22.02
+	Hs
		631458 CROCC_HUMAN (1-1268): 5.14e-34: 146: 13.75		BRD2_HUMAN (115-424): 3.01e-33: 138: 15.39
+	Hs
		518903 TPR_HUMAN (2-620): 2.42e-18: 94.7: 12.04		PHIP_HUMAN (115-637): 1.3e-38: 155: 12.74
+	Hs
		1192496 CNTRL_HUMAN (3-811): 1.27e-16: 89.3: 11.29		CBP_HUMAN (25-238): 1.58e-39: 158: 23.11