HitPredict

Interactor 1: SRSF4 (Q08170)
Serine/arginine-rich splicing factor 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB) (Splicing factor, arginine/serine-rich 4)
Gene: SRSF4

Interactor 2: LAR1B (Q659C4)
La-related protein 1B (La ribonucleoprotein domain family member 1B) (La ribonucleoprotein domain family member 2) (La-related protein 2)
Gene: LARP1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	La~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 494 Hs			1 914
+	Hs
		1061018 SRSF1_HUMAN (3-166): 2.37e-57: 192: 41.42		LAR1B_HUMAN (1-914): 0: 921: 100.00
+	Hs
		1099390 SRSF6_HUMAN (1-180): 4.54e-52: 181: 78.50		LAR1B_HUMAN (1-914): 0: 921: 100.00
+	Hs
		1099113 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		LAR1B_HUMAN (1-914): 0: 921: 100.00
+	Hs
		550323 PABP1_HUMAN (1-189): 3.74e-31: 128: 19.50		LAR1B_HUMAN (1-914): 0: 921: 100.00
+	Hs
		1061024 SRSF1_HUMAN (3-166): 2.37e-57: 192: 41.42		LARP1_HUMAN (3-883): 0: 773: 58.95
+	Hs
		1099400 SRSF6_HUMAN (1-180): 4.54e-52: 181: 78.50		LARP1_HUMAN (3-883): 0: 773: 58.95
+	Hs
		1062019 SRSF4_HUMAN (1-468): 4.58e-48: 174: 100.00		LARP1_HUMAN (3-883): 0: 773: 58.95
+	Hs
		1099125 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		LARP1_HUMAN (3-883): 0: 773: 58.95
+	Hs
		550331 PABP1_HUMAN (1-189): 3.74e-31: 128: 19.50		LARP1_HUMAN (3-883): 0: 773: 58.95
+	Hs
		1061032 SRSF1_HUMAN (3-166): 2.37e-57: 192: 41.42		LARP4_HUMAN (114-703): 1.5e-97: 323: 13.29
+	Hs
		1061076 SRSF1_HUMAN (3-166): 2.37e-57: 192: 41.42		LAR4B_HUMAN (95-701): 2.55e-81: 280: 10.36
+	Hs
		431114 SRSF6_HUMAN (1-180): 4.54e-52: 181: 78.50		LA_HUMAN (215-628): 1.99e-59: 210: 17.78
+	Hs
		431113 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		LA_HUMAN (215-628): 1.99e-59: 210: 17.78
+	Mm
		1053348 SRSF1_MOUSE (3-166): 2.37e-57: 192: 41.42		LARP7_MOUSE (215-603): 7.76e-46: 176: 14.22
+	Hs
		1061006 SRSF1_HUMAN (3-166): 2.37e-57: 192: 41.42		LARP7_HUMAN (215-521): 2.2e-40: 159: 16.72
+	Hs
		1099376 SRSF6_HUMAN (1-180): 4.54e-52: 181: 78.50		LARP7_HUMAN (215-521): 2.2e-40: 159: 16.72
+	Hs
		1062006 SRSF4_HUMAN (1-468): 4.58e-48: 174: 100.00		LARP7_HUMAN (215-521): 2.2e-40: 159: 16.72
+	Hs
		1099101 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		LARP7_HUMAN (215-521): 2.2e-40: 159: 16.72
+	Hs
		1194132 PAP1L_HUMAN (1-189): 1.19e-31: 130: 16.50		LARP7_HUMAN (215-521): 2.2e-40: 159: 16.72
+	Hs
		550310 PABP1_HUMAN (1-189): 3.74e-31: 128: 19.50		LARP7_HUMAN (215-521): 2.2e-40: 159: 16.72