HitPredict

Interactor 1: CDC4 (P07834)
Cell division control protein 4 (E3 ubiquitin ligase complex SCF subunit CDC4) (F-box protein CDC4)
Gene: CDC4

Interactor 2: CG13 (P13365)
G1/S-specific cyclin CLN3
Gene: CLN3

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	22844257, 30080861, 24389104
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000082 - G1/S transition of mitotic cell cycle GO:0005634 - nucleus GO:0051301 - cell division
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 779 Sc			1 580
+	Sc
		431120 CDC4_YEAST (1-779): 0: 553: 100.00		CG23_YEAST (71-306): 6.39e-66: 222: 17.80
+	Hs
		624603 FBXW7_HUMAN (449-777): 4.6e-67: 237: 21.18		CCNE1_HUMAN (4-371): 2.65e-86: 275: 13.28
+	Hs
		943810 FZR1_HUMAN (385-680): 3.82e-35: 142: 14.50		CCNA1_HUMAN (3-343): 1.07e-100: 314: 14.87
+	Mm
		851189 FZR1_MOUSE (385-668): 1.96e-34: 139: 14.42		CCNA2_MOUSE (5-333): 9.14e-99: 308: 15.11
+	Hs
		590235 FZR1_HUMAN (385-680): 3.82e-35: 142: 14.50		CCNA2_HUMAN (4-333): 3.44e-96: 302: 14.11
+	Hs
		538625 FZR1_HUMAN (385-680): 3.82e-35: 142: 14.50		CCNB1_HUMAN (29-348): 7.34e-95: 298: 15.48
+	Mm
		624393 FZR1_MOUSE (385-668): 1.96e-34: 139: 14.42		CCNB1_MOUSE (29-333): 1.63e-93: 295: 15.26
+	Hs
		538630 FBW1A_HUMAN (603-777): 1.43e-28: 123: 13.89		CCNB1_HUMAN (29-348): 7.34e-95: 298: 15.48
+	Hs
		624618 FZR1_HUMAN (385-680): 3.82e-35: 142: 14.50		CCNE1_HUMAN (4-371): 2.65e-86: 275: 13.28
+	Hs
		624620 FBW1A_HUMAN (603-777): 1.43e-28: 123: 13.89		CCNE1_HUMAN (4-371): 2.65e-86: 275: 13.28
+	Sp
		737068 POP1_SCHPO (662-761): 7.63e-09: 61.2: 14.85		CG22_SCHPO (2-364): 3.38e-92: 290: 14.05