HitPredict

Interactor 1: CDC4 (P07834)
Cell division control protein 4 (E3 ubiquitin ligase complex SCF subunit CDC4) (F-box protein CDC4)
Gene: CDC4

Interactor 2: UBC3 (P14682)
Ubiquitin-conjugating enzyme E2-34 kDa (EC 2.3.2.23) (Cell division control protein 34) (E2 ubiquitin-conjugating enzyme 3) (E3 ubiquitin ligase complex SCF subunit CDC34) (Ubiquitin carrier protein) (Ubiquitin-protein ligase)
Gene: CDC34

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.979

The method score is based on:

Property Details
Experiments 9461595, 8943317, 10213692, 20832729, 16338374, 17114057, 17562869, 23645675, 9346239, 20581844, 9636170, 18054791
Identification Methods affinity chromatography technology, pull down, enzymatic study
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains UQ_con~WD40
Common GO terms GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000086 - G2/M transition of mitotic cell cycle
GO:0005634 - nucleus
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0019005 - SCF ubiquitin ligase complex
and 2 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 779
Sc

1 295
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Last updated: 15 Jul 2024