HitPredict

Interactor 1: SUZ12 (Q15022)
Polycomb protein SUZ12 (Chromatin precipitated E2F target 9 protein) (ChET 9 protein) (Joined to JAZF1 protein) (Suppressor of zeste 12 protein homolog)
Gene: SUZ12

Interactor 2: PHF19 (Q5T6S3)
PHD finger protein 19 (Polycomb-like protein 3) (hPCL3)
Gene: PHF19

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.60	0.747

Property	Details
Experiments	24457600, 27705803, 27634302, 23104054, 28514442, 24981860, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0035064 - methylated histone binding GO:0035098 - ESC/E(Z) complex and 1 others more... GO:0046872 - metal ion binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 739 Hs			1 580
+	Mm
		1193527 SUZ12_MOUSE (68-739): 0: 1077: 97.62		PHF19_MOUSE (1-580): 0: 800: 88.79
+	Hs
		1063705 SUZ12_HUMAN (68-739): 0: 1081: 100.00		MTF2_HUMAN (39-578): 0: 631: 46.24
+	Hs
		197988 SUZ12_HUMAN (68-739): 0: 1081: 100.00		PHF1_HUMAN (39-576): 0: 618: 41.39
+	Mm
		970684 SUZ12_MOUSE (68-739): 0: 1077: 97.62		MTF2_MOUSE (17-578): 0: 622: 45.69
+	Hs
		1063662 SUZ12_HUMAN (68-739): 0: 1081: 100.00		ASH2L_HUMAN (186-574): 7.89e-106: 333: 14.60
+	Dm
		1097859 SUZ12_DROME (31-692): 0: 853: 37.92		PCL_DROME (40-462): 2.4e-146: 450: 26.62