HitPredict

Interactor 1: EXOS7 (Q15024)
Exosome complex component RRP42 (Exosome component 7) (Ribosomal RNA-processing protein 42) (p8)
Gene: EXOSC7

Interactor 2: EXOS5 (Q9NQT4)
Exosome complex component RRP46 (Chronic myelogenous leukemia tumor antigen 28) (Exosome component 5) (Ribosomal RNA-processing protein 46) (p12B)
Gene: EXOSC5

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.932

The method score is based on:

Property Details
Experiments 26496610, 24981860, 33961781, 26186194, 28514442
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNase_PH~RNase_PH, RNase_PH~RNase_PH_C, RNase_PH_C~RNase_PH_C
Common GO terms GO:0000175 - 3'-5'-RNA exonuclease activity
GO:0000176 - nuclear exosome (RNase complex)
GO:0000177 - cytoplasmic exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0005634 - nucleus
and 9 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 291
Hs

1 235
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Last updated: 15 Jul 2024