HitPredict

Interactor 1: EXOS7 (Q15024)
Exosome complex component RRP42 (Exosome component 7) (Ribosomal RNA-processing protein 42) (p8)
Gene: EXOSC7

Interactor 2: EXOS3 (Q9NQT5)
Exosome complex component RRP40 (Exosome component 3) (Ribosomal RNA-processing protein 40) (p10)
Gene: EXOSC3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 0.60 0.735

The method score is based on:

Property Details
Experiments 24981860, 33961781, 26186194, 28514442, 20531389, 21255825
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000175 - 3'-5'-RNA exonuclease activity
GO:0000176 - nuclear exosome (RNase complex)
GO:0000177 - cytoplasmic exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0000467 - exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
and 12 others

more...
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 291
Hs

1 275
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024